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Jose Manuel Garcia-Verdugo

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Articles 176
Citations 10822
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Recent Articles
1.
Olmedo-Moreno L, Panadero-Moron C, Sierra-Parraga J, Bueno-Fernandez R, Norton E, Aguilera Y, et al.
Theranostics . 2025 Mar; 15(7):3076-3097. PMID: 40083939
Glioblastoma (GBM) is the most fatal form of brain cancer and its treatment represents a persistent challenge. Mesenchymal stromal cells (MSCs) have been explored as therapeutic tools in cancer management...
2.
Cebrian-Silla A, Nascimento M, Mancia W, Gonzalez-Granero S, Romero-Rodriguez R, Obernier K, et al.
Cell Rep . 2025 Feb; 44(3):115264. PMID: 40019835
Neurogenesis and gliogenesis continue in the ventricular-subventricular zone (V-SVZ) of the adult rodent brain. V-SVZ astroglial cells with apical contact with the ventricle (B1 cells) function as neural stem cells...
3.
Lopez-Cabrera A, Pinero-Perez R, Alvarez-Cordoba M, Cilleros-Holgado P, Gomez-Fernandez D, Reche-Lopez D, et al.
Int J Mol Sci . 2025 Feb; 26(4). PMID: 40003902
One of the most prevalent types of congenital myopathy is nemaline myopathy (NM), which is recognized by histopathological examination of muscle fibers for the presence of "nemaline bodies" (rods). Mutations...
4.
Cilleros-Holgado P, Gomez-Fernandez D, Pinero-Perez R, Romero-Dominguez J, Reche-Lopez D, Alvarez-Cordoba M, et al.
Antioxidants (Basel) . 2025 Feb; 14(2). PMID: 40002401
Ferroptosis, an iron-dependent form of non-apoptotic cell death, is regulated by a complex network involving lipid metabolism, iron homeostasis, and the oxidative-reductive system, with iron accumulation and lipid peroxidation as...
5.
Reche-Lopez D, Romero-Gonzalez A, Alvarez-Cordoba M, Suarez-Carrillo A, Cilleros-Holgado P, Pinero-Perez R, et al.
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39941083
Neurodegeneration with brain iron accumulation (NBIA) involves a group of rare neurogenetic disorders often linked with iron overload in the basal nuclei of the brain presenting with spasticity, dystonia, muscle...
6.
Chen J, Crouch E, Zawadzki M, Jacobs K, Mayo L, Choi J, et al.
Nat Neurosci . 2024 Sep; 27(11):2115-2129. PMID: 39349662
Germinal matrix hemorrhage (GMH) is a devastating neurodevelopmental condition affecting preterm infants, but why blood vessels in this brain region are vulnerable to rupture remains unknown. Here we show that...
7.
Millan I, Perez S, Rius-Perez S, Asensi M, Vento M, Garcia-Verdugo J, et al.
Pediatr Res . 2024 Sep; PMID: 39317699
Background: Preterm infants frequently require oxygen supplementation at birth. However, preterm lung is especially sensible to structural and functional damage caused by oxygen free radicals. Methods: The adaptive mechanisms implied...
8.
Zufiria M, Pikatza-Menoio O, Garciandia-Arcelus M, Bengoetxea X, Jimenez A, Elicegui A, et al.
Acta Neuropathol . 2024 Sep; 148(1):43. PMID: 39283487
Amyotrophic Lateral Sclerosis (ALS) is a multisystemic neurodegenerative disorder, with accumulating evidence indicating metabolic disruptions in the skeletal muscle preceding disease symptoms, rather than them manifesting as a secondary consequence...
9.
Gomez-Fernandez D, Romero-Gonzalez A, Suarez-Rivero J, Cilleros-Holgado P, Alvarez-Cordoba M, Pinero-Perez R, et al.
Antioxidants (Basel) . 2024 Aug; 13(8). PMID: 39199267
Mutations in the () gene are rare inborn errors of metabolism leading to a fatal condition characterized by lipoylation defects of the 2-ketoacid dehydrogenase complexes causing early-onset seizures, psychomotor retardation,...
10.
Cebrian-Silla A, Nascimento M, Mancia W, Gonzalez-Granero S, Romero-Rodriguez R, Obernier K, et al.
bioRxiv . 2024 Jul; PMID: 39005355
Neurogenesis and gliogenesis continue in the Ventricular-Subventricular Zone (V-SVZ) of the adult rodent brain. B1 cells are astroglial cells derived from radial glia that function as primary progenitors or neural...