Jose M Ligos
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Explore the profile of Jose M Ligos including associated specialties, affiliations and a list of published articles.
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10
Citations
82
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Recent Articles
1.
Benito J, Jimenez-Carretero D, Restrepo C, Ligos J, Valentin-Quiroga J, Mahillo I, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38892124
Elite controllers (ECs) are people living with HIV (PLWH) able to control HIV replication without antiretroviral therapy and have been proposed as a model of a functional HIV cure. Much...
2.
Rallon N, Jimenez-Carretero D, Restrepo C, Ligos J, Valentin-Quiroga J, Mahillo I, et al.
J Med Virol
. 2024 May;
96(5):e29646.
PMID: 38699988
Elite controllers (ECs) are an exceptional group of people living with HIV (PLWH) that control HIV replication without therapy. Among the mechanisms involved in this ability, natural killer (NK)-cells have...
3.
Restrepo C, Alvarez B, Valencia J, Garcia M, Navarrete-Munoz M, Ligos J, et al.
J Clin Med
. 2020 Sep;
9(9).
PMID: 32942736
(1) Background: The role of hepatitis C virus (HCV) co-infection on the T-cell homeostasis disturbances in human immunodeficiency virus (HIV)-infected patients as well as its reversion after HCV eradication with...
4.
Garcia M, Navarrete-Munoz M, Ligos J, Cabello A, Restrepo C, Lopez-Bernaldo J, et al.
Sci Rep
. 2018 Oct;
8(1):15541.
PMID: 30341387
A recent study has pointed out to CD32a as a potential biomarker of HIV-persistent CD4 cells. We have characterized the level and phenotype of CD32+ cells contained in different subsets...
5.
Jimenez-Carretero D, Ligos J, Martinez-Lopez M, Sancho D, Montoya M
J Immunol
. 2018 May;
200(10):3319-3331.
PMID: 29735643
Advances in flow cytometry (FCM) increasingly demand adoption of computational analysis tools to tackle the ever-growing data dimensionality. In this study, we tested different data input modes to evaluate how...
6.
Benito J, Ortiz M, Leon A, Sarabia L, Ligos J, Montoya M, et al.
BMC Med
. 2018 Mar;
16(1):30.
PMID: 29490663
Background: Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the...
7.
Perez-Garcia A, Marina-Zarate E, Alvarez-Prado A, Ligos J, Galjart N, Ramiro A
Nat Commun
. 2017 Jul;
8:16067.
PMID: 28677680
In germinal centres (GC) mature B cells undergo intense proliferation and immunoglobulin gene modification before they differentiate into memory B cells or long-lived plasma cells (PC). GC B-cell-to-PC transition involves...
8.
Leiva M, Quintana J, Ligos J, Hidalgo A
Nat Commun
. 2016 Jan;
7:10222.
PMID: 26742601
The life-long maintenance of haematopoietic stem and progenitor cells (HSPCs) critically relies on environmental signals produced by cells that constitute the haematopoietic niche. Here we report a cell-intrinsic mechanism whereby...
9.
Rallon N, Mothe B, Quiros J, Plana M, Ligos J, Montoya M, et al.
AIDS
. 2015 Nov;
30(4):553-62.
PMID: 26558724
Background: The causes of HIV-vaccines failure are poorly understood. Therapeutic vaccination with modified vaccinia Ankara (MVA)-B in HIV-1-infected individuals did not control the virus upon analytical treatment interruption (ATI). We...
10.
Eswaran J, Bernad A, Ligos J, Guinea B, Debreczeni J, Sobott F, et al.
Structure
. 2008 Jan;
16(1):115-24.
PMID: 18184589
The activation segment of protein kinases is structurally highly conserved and central to regulation of kinase activation. Here we report an atypical activation segment architecture in human MPSK1 comprising a...