Jose Luis Soto
Overview
Explore the profile of Jose Luis Soto including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
541
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Recent Articles
11.
Sanchez-Heras A, Castillejo A, Garcia-Diaz J, Robledo M, Teule A, Sanchez R, et al.
Cancers (Basel)
. 2020 Nov;
12(11).
PMID: 33167498
Hereditary leiomyomatosis and renal cell cancer syndrome (HLRCC) is a very rare hereditary disorder characterized by cutaneous leiomyomas (CLMs), uterine leiomyomas (ULMs), renal cysts (RCys) and renal cell cancers (RCCs)....
12.
Damaso E, Canet-Hermida J, Vargas-Parra G, Velasco A, Marin F, Darder E, et al.
Clin Epigenetics
. 2019 Nov;
11(1):171.
PMID: 31779681
Constitutional MLH1 methylation (epimutation) is a rare cause of Lynch syndrome. Low-level methylation (≤ 10%) has occasionally been described. This study aimed to identify low-level constitutional MLH1 epimutations and determine...
13.
Moreno E, Pascual A, Prieto-Cuadra D, Laza V, Molina-Cerrillo J, Ramos-Munoz M, et al.
Cancers (Basel)
. 2019 Mar;
11(3).
PMID: 30862091
microRNAs (miRNA) expression in colorectal (CR) primary tumours can facilitate a more precise molecular characterization. We identified and validated a miRNA profile associated with clinical and histopathological features that might...
14.
Ramirez-Calvo M, Garcia-Casado Z, Fernandez-Serra A, de Juan I, Palanca S, Oltra S, et al.
Hered Cancer Clin Pract
. 2019 Jan;
17:3.
PMID: 30675318
Background: Approximately 5 to 10% of all cancers are caused by inherited germline mutations, many of which are associated with different Hereditary Cancer Syndromes (HCS). In the context of the...
15.
Olivier M, Bouaoun L, Villar S, Robitaille A, Cahais V, Heguy A, et al.
PLoS One
. 2019 Jan;
14(1):e0210372.
PMID: 30653559
Background: In Latin America (LA), there is a high incidence rate of breast cancer (BC) in premenopausal women, and the genomic features of these BC remain unknown. Here, we aim...
16.
Damaso E, Castillejo A, Arias M, Canet-Hermida J, Navarro M, Del Valle J, et al.
Br J Cancer
. 2018 Oct;
119(8):978-987.
PMID: 30283143
Background: Constitutional MLH1 epimutations are characterised by monoallelic methylation of the MLH1 promoter throughout normal tissues, accompanied by allele-specific silencing. The mechanism underlying primary MLH1 epimutations is currently unknown. The...
17.
Soto J, Blanco I, Diez O, Garcia Planells J, Lorda I, Matthijs G, et al.
Med Clin (Barc)
. 2018 Feb;
151(2):80.e1-80.e10.
PMID: 29439875
Genetic diagnosis of hereditary cancer syndromes offers the opportunity to establish more effective predictive and preventive measures for the patient and their families. The ultimate objective is to decrease cancer...
18.
Bellido F, Sowada N, Mur P, Lazaro C, Pons T, Valdes-Mas R, et al.
Gastroenterology
. 2017 Sep;
154(1):181-194.e20.
PMID: 28912018
Background & Aims: Although there is a genetic predisposition to colorectal cancer (CRC), few of the genes that affect risk have been identified. We performed whole-exome sequence analysis of individuals...
19.
Andres-Franch M, Galiana A, Sanchez-Hellin V, Ochoa E, Hernandez-Illan E, Lopez-Garcia P, et al.
PLoS One
. 2017 Mar;
12(3):e0174305.
PMID: 28355283
There is an unambiguous association of Streptococcus gallolyticus infection with colorectal cancer, although there is limited information about epidemiology or interaction between molecular and environmental factors. We performed an original...
20.
Rowlatt A, Hernandez-Suarez G, Sanabria-Salas M, Serrano-Lopez M, Rawlik K, Hernandez-Illan E, et al.
Hum Mol Genet
. 2016 Mar;
25(12):2600-2611.
PMID: 26936820
DNA methylation (DNAm) has been linked to changes in chromatin structure, gene expression and disease. The DNAm level can be affected by genetic variation; although, how this differs by CpG...