Jose Garcia Abreu
Overview
Explore the profile of Jose Garcia Abreu including associated specialties, affiliations and a list of published articles.
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21
Citations
812
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Recent Articles
1.
Varella F, Xavier F, Zanirati G, Goncalves J, Previato T, Pazzin D, et al.
Sci Rep
. 2025 Mar;
15(1):8049.
PMID: 40055364
Focal cortical dysplasia (FCD) is a malformation of cortical development characterized by a heterogeneous group of lesions with high epileptogenic activity. Somatic mutations in the mTOR pathway are the primary...
2.
Marinowic D, Zanirati G, Xavier F, Varella F, Azevedo S, Ghilardi I, et al.
BMC Neurol
. 2023 Sep;
23(1):338.
PMID: 37749503
Background: Focal cortical dysplasia (FCD) is a malformation of cortical development that causes medical refractory seizures, and one of the main treatments may be surgical resection of the affected area...
3.
Bagri K, Oliveira L, Pereira M, Abreu J, Mermelstein C
Cells
. 2022 Nov;
11(21).
PMID: 36359798
Lysosomes are highly dynamic organelles involved in the breakdown and recycling of macromolecules, cell cycle, cell differentiation, and cell death, among many other functions in eukaryotic cells. Recently, lysosomes have...
4.
Almeida J, Lima L, Vieira L, Maside C, Ferreira A, Araujo V, et al.
Cancer Chemother Pharmacol
. 2021 Jan;
87(4):567-578.
PMID: 33471160
Purpose: 5-Fluorouracil (5-FU), an anti-cancer drug, has been used for hepatoblastoma (HB) chemotherapy in children, who may have impaired ovarian follicle pool reserve with lasting effects to reproduction. Therefore, this...
5.
Chen M, Amado N, Tan J, Reis A, Ge M, Abreu J, et al.
Elife
. 2020 Sep;
9.
PMID: 32924931
Wnt signaling through the Frizzled (FZD) family of serpentine receptors is essential for embryogenesis and homeostasis, and stringent control of the FZD protein level is critical for stem cell regulation....
6.
Pentagna N, Da Costa T, Cardoso F, de Almeida F, Blanco Martinez A, Abreu J, et al.
Dev Comp Immunol
. 2020 Aug;
114:103840.
PMID: 32858087
In the present work we have focused on the Histone Deacetylase (HDAC) control of myeloid cells behavior during Xenopus tail regeneration. Here we show that myeloid differentiation is crucial to...
7.
Vieira P, Waghabi M, Beghini D, Predes D, Abreu J, Mouly V, et al.
Front Cell Infect Microbiol
. 2019 Dec;
9:395.
PMID: 31828046
is the causative agent of toxoplasmosis, a parasitic disease with a wide global prevalence. The parasite forms cysts in skeletal muscle cells and neurons, although no evident association with inflammatory...
8.
Amaral L, Martins Ferreira J, Predes D, Abreu J, Noel F, Quintas L
Int J Mol Sci
. 2018 Sep;
19(9).
PMID: 30223494
Bufadienolides are cardiotonic steroids (CTS) identified in mammals. Besides Na⁺/K⁺-ATPase inhibition, they activate signal transduction via protein⁻protein interactions. Diversity of endogenous bufadienolides and mechanisms of action may indicate the presence...
9.
Matias D, Dubois L, Pontes B, Rosario L, Ferrer V, Balca-Silva J, et al.
Mol Neurobiol
. 2018 Jun;
56(2):1517-1530.
PMID: 29948952
Glioblastoma is an extremely aggressive and deadly brain tumor known for its striking cellular heterogeneity and capability to communicate with microenvironment components, such as microglia. Microglia-glioblastoma interaction contributes to an...
10.
Tortelote G, Reis R, de Almeida Mendes F, Abreu J
Cell Signal
. 2017 Aug;
40:30-43.
PMID: 28844868
Wnt signaling refers to a conserved signaling pathway, widely studied due to its roles in cellular communication, cell fate decisions, development and cancer. However, the exact mechanism underlying inhibition of...