Jose C Clemente
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Explore the profile of Jose C Clemente including associated specialties, affiliations and a list of published articles.
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131
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23617
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Recent Articles
1.
Gutzeit C, Grasset E, Matthews D, Maglione P, Britton G, Miller H, et al.
Sci Adv
. 2025 Feb;
11(7):eado9455.
PMID: 39937896
The gut microbiota enhances systemic immunoglobulin G (IgG) responses to vaccines, but it is unknown whether this effect involves IgA, which coats intestinal microbes. That IgA may amplify postimmune IgG...
2.
Scher J, Nayak R, Clemente J
Ann Rheum Dis
. 2025 Jan;
84(1):9-13.
PMID: 39874238
The increasing prevalence of autoimmune and immune-mediated diseases (AIMDs) underscores the need to understand environmental factors that contribute to their pathogenesis, with the microbiome emerging as a key player. Despite...
3.
Bianchimano P, Leone P, Smith E, Gutierrez-Vazquez C, Wind-Andersen E, Bongers G, et al.
Brain Behav Immun
. 2025 Jan;
125:355-370.
PMID: 39826581
Astrocytes play important roles in the central nervous system (CNS) during health and disease. Prior studies have shown that gut commensal-derived indole derivatives as well as secondary bile acids modulate...
4.
Blank R, Bu K, Chen W, Cunningham I, Sokolove J, Lahey L, et al.
medRxiv
. 2025 Jan;
PMID: 39802798
Background: Although genetic factors have been identified in the pathogenesis of rheumatoid arthritis (RA), the concordance rate in monozygotic (MZ) twins is low, suggesting that other features contribute to disease...
5.
Li Z, Harikrishnan L, Xu G, Samanta D, Clemente J, Leng L, et al.
J Med Chem
. 2024 Nov;
68(2):1134-1154.
PMID: 39570797
We describe the identification of selective SMARCA2, VHL-based heterobifunctional degraders. Structurally novel indolo[1,2-]quinazolin-5(7)-one SMARCA bromodomain binders were optimized and then converted to SMARCA2 degraders by linking them to well-defined VHL...
6.
Nyawo G, Naidoo C, Wu B, Kwok B, Clemente J, Li Y, et al.
Microbes Infect
. 2024 Nov;
:105434.
PMID: 39528106
Background: The site-of-disease microbiome and predicted metagenome were evaluated in a cross-sectional study involving people with presumptive tuberculous pericarditis. We also explored the interaction between C-reactive protein (CRP) and the...
7.
Naidoo C, Venter R, Codony F, Agusti G, Kitchin N, Naidoo S, et al.
Sci Rep
. 2024 Sep;
14(1):22350.
PMID: 39333362
DNA characterisation in people with tuberculosis (TB) is critical for diagnostic and microbiome evaluations. However, extracellular DNA, more frequent in people on chemotherapy, confounds results. We evaluated whether nucleic acid...
8.
Chiyaka T, Nyawo G, Naidoo C, Moodley S, Clemente J, Malherbe S, et al.
Ann Clin Microbiol Antimicrob
. 2024 Aug;
23(1):74.
PMID: 39175010
Background: Tuberculosis (TB), a major cause of disease and antimicrobial resistance, is spread via aerosols. Aerosols have diagnostic potential and airborne-microbes other than Mycobacterium tuberculosis complex (MTBC) may influence transmission....
9.
Moodley S, Kroon E, Naidoo C, Nyawo G, Wu B, Naidoo S, et al.
Microorganisms
. 2024 Jun;
12(6).
PMID: 38930430
Latent tuberculosis infection (LTBI) is common in people living with HIV (PLHIV) in high-TB-burden settings. Active TB is associated with specific stool taxa; however, little is known about the stool...
10.
Nyawo G, Naidoo C, Wu B, Kwok B, Clemente J, Li Y, et al.
medRxiv
. 2024 May;
PMID: 38712063
Background: The microbiome likely plays a role in tuberculosis (TB) pathogenesis. We evaluated the site-of-disease microbiome and predicted metagenome in people with presumptive tuberculous pericarditis, a major cause of mortality,...