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Jose A Crespo

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Citations 301
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Recent Articles
1.
Satue M, Rodrigo M, Obis J, Vilades E, Gracia H, Otin S, et al.
Invest Ophthalmol Vis Sci . 2017 Feb; 58(2):1151-1157. PMID: 28208185
Purpose: To quantify changes in visual function parameters and in the retinal nerve fiber layer and macular thickness over a 5-year period in patients with Parkinson's disease (PD). Methods: Thirty...
2.
Graus F, Bruna J, Pardo J, Escudero D, Vilas D, Barcelo I, et al.
Neuro Oncol . 2013 Mar; 15(6):797-805. PMID: 23460319
Background: To assess management patterns and outcome in patients with glioblastoma multiforme (GBM) treated during 2008-2010 in Spain. Methods: Retrospective analysis of clinical, therapeutic, and survival data collected through filled...
3.
Crespo J, Stockl P, Ueberall F, Jenny M, Saria A, Zernig G
PLoS One . 2012 Feb; 7(2):e30502. PMID: 22348011
One of the greatest challenges in the treatment of substance dependence is to reverse the control that drug-associated stimuli have gained over the addict's behavior, as these drug-associated memories increase...
4.
Garcia-Lecumberri C, Torres I, Martin S, Crespo J, Miguens M, Nicanor C, et al.
J Psychopharmacol . 2010 May; 25(6):783-91. PMID: 20488829
Dose-response studies are thought to be a valuable tool to predict the most genetically drug-vulnerable individuals. However, dose-response curves for morphine self-administration have not yet been examined and nor strain...
5.
Crespo J, Stockl P, Zorn K, Saria A, Zernig G
Neuropsychopharmacology . 2008 Apr; 33(13):3213-20. PMID: 18418362
Acquisition of drug-reinforced behavior is accompanied by a systematic increase of release of the neurotransmitter acetylcholine (ACh) rather than dopamine, the expected prime reward neurotransmitter candidate, in the nucleus accumbens...
6.
Zernig G, Ahmed S, Cardinal R, Morgan D, Acquas E, Foltin R, et al.
Pharmacology . 2007 Jun; 80(2-3):65-119. PMID: 17570954
Escalation of drug use, a hallmark of drug dependence, has traditionally been interpreted as reflecting the development of tolerance to the drug's effects. However, on the basis of animal behavioral...
7.
Crespo J, Panlilio L, Schindler C, Sturm K, Saria A, Zernig G
Ann N Y Acad Sci . 2006 Nov; 1074:497-504. PMID: 17105948
An individual's drug abuse pattern is determined by a multitude of factors. Among these, simple pharmacological determinants of within-binge drug consumption are sorely underinvestigated. We therefore determined if within-session operant...
8.
Madlung E, Haring C, Crespo J, Saria A, Grubinger P, Zernig G
Pharmacology . 2006 Aug; 78(1):38-43. PMID: 16912515
Escalation of drug use by addicts has traditionally been interpreted as tolerance to the drug's effects. On the basis of animal behavioral data, several groups have recently proposed alternative explanations,...
9.
Crespo J, Sturm K, Saria A, Zernig G
J Neurosci . 2006 Jun; 26(22):6004-10. PMID: 16738243
Neurotransmitter release in the nucleus accumbens core (NACore) during the acquisition of remifentanil or cocaine reinforcement was determined in an operant runway procedure by simultaneous tandem mass spectrometric analysis of...
10.
Crespo J, Sturm K, Saria A, Zernig G
Psychopharmacology (Berl) . 2005 Oct; 183(2):201-9. PMID: 16220330
Rationale: The ultra-short-acting mu opioid agonist analgesic/anesthetic remifentanil (RMF) is extremely rapidly eliminated from blood (half-life in rats, 0.3-0.7 min). This extremely fast elimination is thought to be the main...