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Joscha Kandels

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Recent Articles
1.
Kandels J, Stobe S, Marshall R, Hagendorff A, Metze M
J Cardiovasc Dev Dis . 2024 Sep; 11(9). PMID: 39330342
Background: Left atrial strain (LAS) assessment by speckle tracking echocardiography (STE) has been shown to be a remarkable means of quantifying LA function as an early marker of LV pathology....
2.
Kandels J, Denk V, Pedersen M, Kragholm K, Sogaard P, Tayal B, et al.
Clin Res Cardiol . 2024 Aug; PMID: 39102001
Background: Cardiac magnetic resonance imaging (cMRI) is considered the gold standard for the assessment of left ventricular (LV) systolic function. However, discrepancies have been reported in the literature between LV...
3.
Kandels J, Pawluczuk J, Stobe S, Hagendorff A
Int J Cardiovasc Imaging . 2024 May; 40(9):2007-2013. PMID: 38780708
Background: Transthoracic echocardiography is usually the first non-invasive imaging modality for the detection of Loeffler endocarditis at thrombotic stage. In the recent decade 3D echocardiography and deformation imaging already proved...
4.
Kandels J, Richter S, Hagendorff A, Kragholm K, Tayal B, Laufs U, et al.
Front Cardiovasc Med . 2024 Jan; 10:1322145. PMID: 38264261
Purpose: Cardiac magnetic resonance imaging (cMRI) represents the gold standard to detect myocarditis. Left ventricular (LV) deformation imaging provides additional diagnostic options presumably exceeding conventional transthoracic echocardiography (TTE). The present...
5.
Kandels J, Metze M, Hagendorff A, Stobe S
J Clin Med . 2023 Dec; 12(24). PMID: 38137763
Background: A reduced global myocardial work index (GWI) ≤ 1951 mmHg% is associated with increased mortality in patients with severe aortic valve stenosis (AS). However, parameters predicting the outcome in...
6.
Kandels J, Metze M, Hagendorff A, Stobe S
Diagnostics (Basel) . 2023 Jun; 13(11). PMID: 37296679
Background: Diagnosing severe aortic stenosis (AS) depends on flow and pressure conditions. It is suspected that concomitant aortic regurgitation (AR) has an impact on the assessment of AS severity. The...
7.
Hagendorff A, Kandels J, Metze M, Tayal B, Stobe S
Diagnostics (Basel) . 2023 Apr; 13(7). PMID: 37046577
The analysis of left ventricular function is predominantly based on left ventricular volume assessment. Especially in valvular heart diseases, the quantitative assessment of total and effective stroke volumes as well...
8.
Stobe S, Kandels J, Metze M, Tayal B, Laufs U, Hagendorff A
Front Cardiovasc Med . 2023 Jan; 9:1101493. PMID: 36704453
Aims: Predictors of progression of moderate aortic valve stenosis (AS) are incompletely understood. The objective of this study was to evaluate the prognostic value of left ventricular hypertrophy (LVH), diastolic...
9.
Gehlen J, Stundl A, Debiec R, Fontana F, Krane M, Sharipova D, et al.
Cardiovasc Res . 2022 Jun; 119(3):857-866. PMID: 35727948
Aims: The present study aims to characterize the genetic risk architecture of bicuspid aortic valve (BAV) disease, the most common congenital heart defect. Methods And Results: We carried out a...
10.
Lavall D, Kuprat L, Kandels J, Stobe S, Hagendorff A, Laufs U
Int J Cardiovasc Imaging . 2020 Jan; 36(4):605-614. PMID: 31933102
Patients with severe aortic stenosis are classified according to flow-gradient patterns. We investigated whether left ventricular (LV) mechanical dispersion, a marker of dyssynchrony and predictor of mortality, is associated with...