Jorge Lazaro
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Explore the profile of Jorge Lazaro including associated specialties, affiliations and a list of published articles.
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9
Citations
239
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Recent Articles
1.
Matsuda M, Lazaro J, Ebisuya M
Nat Commun
. 2025 Jan;
16(1):845.
PMID: 39833174
Numerous cellular and molecular processes during embryonic development prompt the fundamental question of how their tempos are coordinated and whether a common global modulator exists. While the segmentation clock tempo...
2.
G Garcia-Ruiz De Morales A, Vivancos M, Lazaro J, Romero Hernandez B, Mateos B, Perez-Elias P, et al.
Biomedicines
. 2024 Aug;
12(8).
PMID: 39200310
Despite remarkable improvement in the human immunodeficiency virus (HIV) and hepatitis C virus (HCV) care continuum, the rate of late diagnosis of HIV and HCV in high-income countries remains unacceptably...
3.
Harry C, Hibshman J, Damatac 2nd A, Davidson P, Estermann M, Flores-Flores M, et al.
STAR Protoc
. 2024 Aug;
5(3):103232.
PMID: 39128009
Tardigrades are microscopic organisms with exceptional resilience to environmental extremes. Most protocols to visualize the internal anatomy of tardigrades rely on fixation, hampering our understanding of dynamic changes to organelles...
4.
Lazaro J, Sochacki J, Ebisuya M
Curr Opin Genet Dev
. 2024 Jan;
84:102149.
PMID: 38199063
The rate of development is highly variable across animal species. However, the mechanisms regulating developmental tempo have remained elusive due to difficulties in performing direct interspecies comparisons. Here, we discuss...
5.
Lazaro J, Costanzo M, Sanaki-Matsumiya M, Girardot C, Hayashi M, Hayashi K, et al.
Cell Stem Cell
. 2023 Jun;
30(7):938-949.e7.
PMID: 37343565
Differential speeds in biochemical reactions have been proposed to be responsible for the differences in developmental tempo between mice and humans. However, the underlying mechanism controlling the species-specific kinetics remains...
6.
Lazaro J, Jansen G, Yang Y, Torres-Acosta M, Lye G, Oliver S, et al.
Front Mol Biosci
. 2022 May;
9:855735.
PMID: 35573743
The current production of a number of commodity chemicals relies on the exploitation of fossil fuels and hence has an irreversible impact on the environment. Biotechnological processes offer an attractive...
7.
Sagner A, Zhang I, Watson T, Lazaro J, Melchionda M, Briscoe J
PLoS Biol
. 2021 Nov;
19(11):e3001450.
PMID: 34767545
The molecular mechanisms that produce the full array of neuronal subtypes in the vertebrate nervous system are incompletely understood. Here, we provide evidence of a global temporal patterning program comprising...
8.
Rayon T, Stamataki D, Perez-Carrasco R, Garcia-Perez L, Barrington C, Melchionda M, et al.
Science
. 2020 Sep;
369(6510).
PMID: 32943498
Although many molecular mechanisms controlling developmental processes are evolutionarily conserved, the speed at which the embryo develops can vary substantially between species. For example, the same genetic program, comprising sequential...
9.
Dufourt J, Trullo A, Hunter J, Fernandez C, Lazaro J, Dejean M, et al.
Nat Commun
. 2019 Jan;
10(1):315.
PMID: 30644405
The original version of this Article contained an error in Fig. 4a, in which the "=" sign of the equation was inadvertently replaced with a "-" sign. This has been...
10.
Dufourt J, Trullo A, Hunter J, Fernandez C, Lazaro J, Dejean M, et al.
Nat Commun
. 2018 Dec;
9(1):5194.
PMID: 30518940
Pioneer transcription factors can engage nucleosomal DNA, which leads to local chromatin remodeling and to the establishment of transcriptional competence. However, the impact of enhancer priming by pioneer factors on...