Jorge A Carvajal
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Explore the profile of Jorge A Carvajal including associated specialties, affiliations and a list of published articles.
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20
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101
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Recent Articles
11.
Carvajal J
Exp Physiol
. 2014 Jan;
99(3):489-94.
PMID: 24443352
Myometrial quiescence is a physiological stage of the myometrium during pregnancy. It is a period of active relaxation of the myometrial smooth muscle cells; myometrial quiescence is responsible for maintaining...
12.
Carvajal J, Delpiano A, Cuello M, Poblete J
Reprod Sci
. 2012 Sep;
20(5):597-604.
PMID: 23012317
Brain natriuretic peptide (BNP) is synthesized by human fetal membranes, both the amnion and chorion. This locally produced BNP inhibits the contraction of the human myometrium, contributing to the maintenance...
13.
Jofre N, Delpiano A, Cuello M, Poblete J, Vargas P, Carvajal J
Reprod Sci
. 2012 Aug;
20(1):69-77.
PMID: 22872490
We postulate that protein kinase C α (PKCα) may contribute to the maintenance of pregnancy myometrial quiescence in humans. We studied the changes in myometrial PKCα gene products (messenger RNA...
14.
Carvajal J, Delpiano A, Cuello M, Poblete J, Casanello P, Sobrevia L, et al.
Reprod Sci
. 2009 Jan;
16(1):32-42.
PMID: 19144889
We aim to demonstrate that Brain Natriuretic Peptide (BNP) is synthesized and released from the fetal membranes and mediates pregnancy myometrial quiescence. Myometrium and fetal membranes (FM) were obtained from...
15.
Donoso E, Carvajal J
Maturitas
. 2008 May;
59(4):381-6.
PMID: 18482808
Unlabelled: Pregnancy in the older woman is a well-known risk factor for perinatal morbidity and mortality. Objective: To evaluate perinatal and infant morbidity and mortality in women 50 or more...
16.
Carvajal J, Vera C, Vargas P, Jordan F, Patillo A, Oyarzun E
Rev Med Chil
. 2007 Jun;
135(4):436-42.
PMID: 17554451
Background: Fetal growth restriction (FGR) is associated with increased risk of perinatal morbidity or death. Nationwide implementation of new fetal growth charts, requires a lower fetal weight for the diagnosis...
17.
Carvajal J, Vidal R, Cuello M, Poblete J, Weiner C
J Soc Gynecol Investig
. 2006 Jul;
13(5):343-9.
PMID: 16814163
Objective: To test the hypothesis that fetal membranes (chorion or amnion) release one or more factors responsible for myometrial quiescence. Methods: Myometrial samples were excised from women at elective term...
18.
Germain A, Kato S, Carvajal J, Valenzuela G, Valdes G, Glasinovic J
Am J Obstet Gynecol
. 2003 Oct;
189(2):577-82.
PMID: 14520238
Objective: We tested the hypothesis that during intrahepatic cholestasis of pregnancy bile acids activate the myometrial oxytocin receptor pathway. Study Design: Myometrial sensitivity to oxytocin and oxytocin-receptor messenger RNA and...
19.
Carvajal J, Thompson L, Weiner C
Am J Obstet Gynecol
. 2003 Jan;
188(1):84-91.
PMID: 12548200
Objective: We previously demonstrated that chorion releases a factor that inhibits both spontaneous and oxytocin-stimulated myometrial contractility. Here, we investigate the mechanism of action of this unidentified substance. Study Design:...
20.
Germain A, Carvajal J, Glasinovic J, Kato C S, Williamson C
J Soc Gynecol Investig
. 2002 Feb;
9(1):10-4.
PMID: 11839502
Objective: To review animal and human data available regarding the etiology, maternal and fetal impact, and treatment of intrahepatic cholestasis of pregnancy (ICP). Methods: Pertinent studies on human and animal...