Jorge A Bezerra
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Explore the profile of Jorge A Bezerra including associated specialties, affiliations and a list of published articles.
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98
Citations
2716
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Recent Articles
1.
Taylor S, Harpavat S, Gromer K, Andreev V, Loomes K, Bezerra J, et al.
Pediatr Res
. 2025 Jan;
PMID: 39881181
Background: The immune heterogeneity of biliary atresia (BA) presents a challenge for development of prognostic biomarkers. This study aimed to identify early immune signatures associated with biliary drainage after Kasai...
2.
Pandurangi S, Mourya R, Nalluri S, Fei L, Dong S, Harpavat S, et al.
Hepatology
. 2024 Mar;
80(1):152-162.
PMID: 38446707
Background And Aims: High levels of serum matrix metalloproteinase-7 (MMP-7) have been linked to biliary atresia (BA), with wide variation in concentration cutoffs. We investigated the accuracy of serum MMP-7...
3.
Squires J, Miethke A, Valencia C, Hawthorne K, Henn L, Van Hove J, et al.
Hepatol Commun
. 2023 May;
7(6).
PMID: 37184518
Background: Alterations in both mitochondrial DNA (mtDNA) and nuclear DNA genes affect mitochondria function, causing a range of liver-based conditions termed mitochondrial hepatopathies (MH), which are subcategorized as mtDNA depletion,...
4.
Peters A, Kim S, Mourya R, Asai A, Taylor A, Rogers M, et al.
J Pediatr
. 2023 Apr;
259:113439.
PMID: 37088181
Objective: To evaluate whether the nature and severity of non-A-E severe acute hepatitis in children noted by the World Health Organization from late 2021 through early 2022 was indeed increased...
5.
Russi A, Shivakumar P, Luo Z, Bezerra J
Hepatology
. 2023 Apr;
78(4):1035-1049.
PMID: 37078450
Background And Aims: Although a dysregulated type 1 immune response is integral to the pathogenesis of biliary atresia, studies in both humans and mice have uncovered a type 2 response,...
6.
Felzen A, van Wessel D, Gonzales E, Thompson R, Jankowska I, Shneider B, et al.
JHEP Rep
. 2023 Jan;
5(2):100626.
PMID: 36687469
Background & Aims: Bile salt export pump (BSEP) deficiency frequently necessitates liver transplantation in childhood. In contrast to two predicted protein truncating mutations (PPTMs), homozygous p.D482G or p.E297G mutations are...
7.
Pandurangi S, Kim S, Asai A, Bondoc A, Balistreri W, Campbell K, et al.
J Pediatr Surg
. 2022 Dec;
58(8):1483-1488.
PMID: 36496264
Background: Controversies in management of biliary atresia (BA) after hepatoportoenterostomy (HPE) lead to variable treatment protocols. We implemented standardized medical management after HPE, customizing the use of antibiotics and corticosteroids...
8.
Harpavat S, Hawthorne K, Setchell K, Narvaez Rivas M, Henn L, Beil C, et al.
Hepatology
. 2022 Sep;
77(3):862-873.
PMID: 36131538
Background And Aims: In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP). Infants with persistently high levels invariably need liver transplant, but those achieving...
9.
Leung D, Devaraj S, Goodrich N, Chen X, Rajapakshe D, Andreev V, et al.
Hepatology
. 2022 Sep;
77(2):530-545.
PMID: 36069569
Background And Aims: Detailed investigation of the biological pathways leading to hepatic fibrosis and identification of liver fibrosis biomarkers may facilitate early interventions for pediatric cholestasis. Approach And Results: A...
10.
Shneider B, Kamath B, Magee J, Goodrich N, Loomes K, Ye W, et al.
Hepatol Commun
. 2022 May;
6(8):1910-1921.
PMID: 35506349
The conduct of long-term conventional randomized clinical trials in rare diseases is very difficult, making evidenced-based drug development problematic. As a result, real-world data/evidence are being used more frequently to...