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Jordi Alberch

Explore the profile of Jordi Alberch including associated specialties, affiliations and a list of published articles. Areas
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Articles 135
Citations 3045
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Recent Articles
1.
Sancho-Balsells A, Brito V, Fernandez B, Pardo M, Straccia M, Gines S, et al.
Front Cell Neurosci . 2025 Jan; 18():1542681. PMID: 39839352
[This corrects the article DOI: 10.3389/fncel.2020.00093.].
2.
Ballasch I, Lopez-Molina L, Galan-Ganga M, Sancho-Balsells A, Rodriguez-Navarro I, Borras-Pernas S, et al.
J Neuroinflammation . 2024 Dec; 21(1):326. PMID: 39695786
Schizophrenia is a complex multifactorial disorder and increasing evidence suggests the involvement of immune dysregulations in its pathogenesis. We observed that IKZF1 and IKZF2, classic immune-related transcription factors (TFs), were...
3.
Shen Y, Zaballa S, Bech X, Sancho-Balsells A, Rodriguez-Navarro I, Cifuentes-Diaz C, et al.
Cell Stem Cell . 2024 Oct; 31(12):1741-1759.e8. PMID: 39426381
Yamanaka factors (YFs) can reverse some aging features in mammalian tissues, but their effects on the brain remain largely unexplored. Here, we induced YFs in the mouse brain in a...
4.
Conde-Berriozabal S, Sitja-Roqueta L, Garcia-Garcia E, Garcia-Gilabert L, Sancho-Balsells A, Fernandez-Garcia S, et al.
Exp Neurol . 2024 Oct; 383:114991. PMID: 39389161
The alterations in the basal ganglia circuitry are core pathological hallmark in Huntington's Disease (HD) and traditionally linked to its sever motor symptoms. Recently it was shown that optogenetic stimulation...
5.
Campoy-Campos G, Solana-Balaguer J, Guisado-Corcoll A, Chicote-Gonzalez A, Garcia-Segura P, Perez-Sisques L, et al.
Nucleic Acids Res . 2024 Sep; 52(18):11158-11176. PMID: 39268577
RTP801/REDD1 is a stress-responsive protein overexpressed in neurodegenerative diseases such as Alzheimer's disease (AD) that contributes to cognitive deficits and neuroinflammation. Here, we found that RTP801 interacts with HSPC117, DDX1...
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Garcia-Garcia E, Carreras-Caballe M, Coll-Manzano A, Ramon-Lainez A, Besa-Selva G, Perez-Navarro E, et al.
Front Neurosci . 2024 Jun; 18:1394478. PMID: 38903599
VPS13A disease and Huntington's disease (HD) are two basal ganglia disorders that may be difficult to distinguish clinically because they have similar symptoms, neuropathological features, and cellular dysfunctions with selective...
8.
Solana-Balaguer J, Garcia-Segura P, Campoy-Campos G, Chicote-Gonzalez A, Fernandez-Irigoyen J, Santamaria E, et al.
Cell Commun Signal . 2024 Jun; 22(1):321. PMID: 38863004
Huntington's disease (HD) is a neurological disorder caused by a CAG expansion in the Huntingtin gene (HTT). HD pathology mostly affects striatal medium-sized spiny neurons and results in an altered...
9.
Lopez-Molina L, Sancho-Balsells A, Al-Massadi O, Montalban E, Alberch J, Arranz B, et al.
Neurobiol Dis . 2024 Mar; 194:106487. PMID: 38552722
Pyk2 has been shown previously to be involved in several psychological and cognitive alterations related to stress, Huntington's disease, and Alzheimer's disease. All these disorders are accompanied by different types...
10.
Sancho-Balsells A, Borras-Pernas S, Flotta F, Chen W, Del Toro D, Rodriguez M, et al.
J Affect Disord . 2024 Mar; 354:574-588. PMID: 38490587
Background: Chronic stress is an important risk factor for the development of major depressive disorder (MDD). Recent studies have shown microbiome dysbiosis as one of the pathogenic mechanisms associated with...