Jordan J Bartlett
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Explore the profile of Jordan J Bartlett including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
295
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Recent Articles
1.
Trivedi P, Bartlett J, Mercer A, Slade L, Surette M, Ballabio A, et al.
Biochim Biophys Acta Mol Basis Dis
. 2020 May;
1866(10):165832.
PMID: 32437957
Glucolipotoxicity following nutrient overload causes cardiomyocyte injury by inhibiting TFEB and suppressing lysosomal function. We ascertained whether in addition to the amount, the type of fatty acids (FAs) and duration...
2.
Trivedi P, Bartlett J, Pulinilkunnil T
Cells
. 2020 May;
9(5).
PMID: 32375321
Lysosomes are the main proteolytic compartments of mammalian cells comprising of a battery of hydrolases. Lysosomes dispose and recycle extracellular or intracellular macromolecules by fusing with endosomes or autophagosomes through...
3.
Bartlett J, Trivedi P, Pulinilkunnil T
J Mol Cell Cardiol
. 2017 Jan;
104:1-8.
PMID: 28108310
Doxorubicin (DOX)-induced cardiotoxicity has been a well-known phenomenon to clinicians and scientists for decades; however, molecular mechanisms underlying DOX cardiotoxicity are still being uncovered. Although the majority of prior research...
4.
Trivedi P, Bartlett J, Perez L, Brunt K, Legare J, Hassan A, et al.
Biochim Biophys Acta
. 2016 Sep;
1861(12 Pt A):1893-1910.
PMID: 27620487
Impaired cardiac metabolism in the obese and diabetic heart leads to glucolipotoxicity and ensuing cardiomyopathy. Glucolipotoxicity causes cardiomyocyte injury by increasing energy insufficiency, impairing proteasomal-mediated protein degradation and inducing apoptosis....
5.
Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T
Biochem J
. 2016 Aug;
473(21):3769-3789.
PMID: 27487838
Doxorubicin (DOX) is an effective anti-cancer agent. However, DOX treatment increases patient susceptibility to dilated cardiomyopathy. DOX predisposes cardiomyocytes to insult by suppressing mitochondrial energy metabolism, altering calcium flux, and...