Joo-Hyung Lee
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Explore the profile of Joo-Hyung Lee including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
810
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Recent Articles
1.
Wang R, Lee J, Kim J, Xiong F, Hasani L, Shi Y, et al.
Nat Microbiol
. 2023 Mar;
8(4):679-694.
PMID: 36959507
Some viruses restructure host chromatin, influencing gene expression, with implications for disease outcome. Whether this occurs for SARS-CoV-2, the virus causing COVID-19, is largely unknown. Here we characterized the 3D...
2.
Son S, Kim H, Lim H, Lee J, Lee K, Shin I
Cell Death Dis
. 2023 Feb;
14(2):81.
PMID: 36737605
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. TNBC patients typically exhibit unfavorable outcomes due to its rapid growth and metastatic potential. Here, we found overexpression...
3.
Zhu X, Qi C, Wang R, Lee J, Shao J, Bei L, et al.
Cell Rep
. 2022 Nov;
41(5):111576.
PMID: 36323253
The nuclear pore complex (NPC) comprises more than 30 nucleoporins (NUPs) and is a hallmark of eukaryotes. NUPs have been suggested to be important in regulating gene transcription and 3D...
4.
Choi K, Quan M, Qi C, Lee J, Tsoi P, Zahabiyon M, et al.
Nat Cell Biol
. 2022 Apr;
24(5):737-747.
PMID: 35484250
Human NANOG expression resets stem cells to ground-state pluripotency. Here we identify the unique features of human NANOG that relate to its dose-sensitive function as a master transcription factor. NANOG...
5.
Lee J, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen P, et al.
Mol Cell
. 2021 Aug;
81(16):3368-3385.e9.
PMID: 34375583
The mechanistic understanding of nascent RNAs in transcriptional control remains limited. Here, by a high sensitivity method methylation-inscribed nascent transcripts sequencing (MINT-seq), we characterized the landscapes of N6-methyladenosine (m6A) on...
6.
Wang R, Lee J, Xiong F, Kim J, Hasani L, Yuan X, et al.
bioRxiv
. 2021 Jul;
PMID: 34312624
SARS-CoV-2 has made >190-million infections worldwide, thus it is pivotal to understand the viral impacts on host cells. Many viruses can significantly alter host chromatin , but such roles of...
7.
Xiong F, Wang R, Lee J, Li S, Chen S, Liao Z, et al.
Cell Res
. 2021 Jun;
31(8):861-885.
PMID: 34108665
The molecular basis underlying the interaction between retrotransposable elements (RTEs) and the human genome remains poorly understood. Here, we profiled N-methyladenosine (mA) deposition on nascent RNAs in human cells by...
8.
Oh S, Shao J, Mitra J, Xiong F, DAntonio M, Wang R, et al.
Nature
. 2021 May;
595(7869):735-740.
PMID: 34040254
The functional engagement between an enhancer and its target promoter ensures precise gene transcription. Understanding the basis of promoter choice by enhancers has important implications for health and disease. Here...
9.
Jung S, Kim H, Wi E, Kong J, Lee J, Song K, et al.
J Nanosci Nanotechnol
. 2021 Mar;
21(9):4735-4739.
PMID: 33691859
Recently, the technology of the industry has been increasing for diffractive optical elements, holograms, optical components, and next-generation display components. The advanced high value-added industry is designing fine patterns on...
10.
Liao Z, Lee J, Krakowiak J, Wang R, Li W
J Vis Exp
. 2020 Jun;
(160).
PMID: 32568241
Enhancers are pivotal genomic elements scattered through the mammalian genome and dictate tissue-specific gene expression programs. Increasing evidence has shown that enhancers not only provide DNA binding motifs for transcription...