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Jonne J Sikkens

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Citations 454
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Recent Articles
1.
Smulders Y, Sikkens J
Ned Tijdschr Geneeskd . 2025 Jan; 169. PMID: 39840585
This sentence often concludes medical research articles. We argue that 'more research is needed' is an empty phrase. There is always room for synthesis of previously existing and currently added...
2.
Hooftman J, Zwaan L, Sikkens J, Schouten B, de Bruijne M, Wagner C
Diagnosis (Berl) . 2024 Nov; PMID: 39588855
Objectives: To investigate longitudinal trends in the incidence, preventability, and causes of DAEs (diagnostic adverse events) between 2008 and 2019 and compare DAEs to other AE (adverse event) types. Methods:...
3.
de Jonge N, Janssen J, Ypma P, Herbers A, de Kreuk A, Vasmel W, et al.
Support Care Cancer . 2024 Aug; 32(9):579. PMID: 39115709
Purpose: Haematology patients with high-risk neutropenia are prone to mucosal-barrier injury-associated laboratory-confirmed bloodstream infections (MBI-LCBI). We assessed risk factors for MBI-LCBI including candidaemia in neutropenic haematology patients with fever. Methods:...
4.
Overgaauw A, Ligthart M, Azilji K, Minderhoud T, Sikkens J, Biesheuvel T, et al.
Acute Med . 2024 Apr; 23(1):4-10. PMID: 38619164
Background And Importance: Long waiting times in the emergency department (ED) is an increasing problem in the recent years and is expected to become an even bigger problem in the...
5.
Timmerman A, Commandeur L, Deijs M, Burggraaff M, Lavell A, van der Straten K, et al.
Viruses . 2024 Jan; 16(1). PMID: 38257799
Members of the family dominate the blood virome, emerging early in life. The anellome, representing the variety of anelloviruses within an individual, stabilizes by adulthood. Despite their supposedly commensal nature,...
6.
Serne E, Sikkens J, IJzerman R
Ned Tijdschr Geneeskd . 2023 Nov; 167. PMID: 37930171
In persons with type 2 diabetes without established cardiovascular complications data are lacking on the comparative effectiveness of commonly used glucose-lowering medications, when added to metformin, with respect to glycemic...
7.
Lavell A, Tijdink J, Buis D, Smulders Y, Bomers M, Sikkens J
PLoS One . 2023 Aug; 18(8):e0288352. PMID: 37531335
Background: Hospital health care workers (HCW) are at increased risk of contracting SARS-CoV-2. We investigated whether certain behavioral and physical features, e.g. nose picking and wearing glasses, are associated with...
8.
Guo L, Appelman B, Mooij-Kalverda K, Houtkooper R, van Weeghel M, Vaz F, et al.
EBioMedicine . 2023 Jul; 94:104729. PMID: 37506544
Background: Post-acute sequela of SARS-CoV-2 infection (PASC) encompass fatigue, post-exertional malaise and cognitive problems. The abundant expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase-2 (IDO2) in fatal/severe COVID-19, led us to...
9.
Lavell A, Sikkens J, Edridge A, van der Straten K, Sechan F, Oomen M, et al.
iScience . 2022 Sep; 25(10):105105. PMID: 36101832
Antibodies against seasonal human coronaviruses (HCoVs) are known to cross-react with SARS-CoV-2, but data on cross-protective effects of prior HCoV infections are conflicting. In a prospective cohort of healthcare workers...
10.
van der Straten K, Guerra D, van Gils M, Bontjer I, Caniels T, van Willigen H, et al.
Immunity . 2022 Aug; 55(9):1725-1731.e4. PMID: 35973428
Large-scale vaccination campaigns have prevented countless hospitalizations and deaths due to COVID-19. However, the emergence of SARS-CoV-2 variants that escape from immunity challenges the effectiveness of current vaccines. Given this...