Jongpil Kim
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Explore the profile of Jongpil Kim including associated specialties, affiliations and a list of published articles.
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68
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3015
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Recent Articles
1.
Kim H, Cho B, Kim H, Kang S, An S, Kwon D, et al.
Nat Commun
. 2025 Mar;
16(1):2435.
PMID: 40069581
Mania is a complex psychiatric disease characterized by hyperactivity, elevated mood and reduced anxiety. Despite extensive studies on the mechanism of the manic episodes, the molecular targets that control manic...
2.
Kim H, Kang S, Cho B, An S, Kim Y, Kim J
Adv Sci (Weinh)
. 2025 Feb;
:e2412548.
PMID: 39965129
Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons and the accumulation of α-synuclein aggregates, yet current models inadequately mimic the complex human brain environment. Recent advances...
3.
Cho B, Kim J, Kim S, An S, Hwang Y, Kim Y, et al.
Adv Sci (Weinh)
. 2024 Sep;
11(41):e2403105.
PMID: 39279468
Direct lineage reprogramming into dopaminergic (DA) neurons holds great promise for the more effective production of DA neurons, offering potential therapeutic benefits for conditions such as Parkinson's disease. However, the...
4.
Kim Y, Kim H, Cho B, An S, Kang S, Kim S, et al.
Front Aging Neurosci
. 2024 Aug;
16:1435445.
PMID: 39185458
Brain organoids have become a valuable tool for studying human brain development, disease modeling, and drug testing. However, generating brain organoids with mature neurons is time-intensive and often incomplete, limiting...
5.
Oh J, Lee H, Jang S, Kim H, Park G, Serikov A, et al.
Adv Sci (Weinh)
. 2024 Aug;
11(43):e2403245.
PMID: 39119926
Despite clinical data stretching over millennia, the neurobiological basis of the effectiveness of acupuncture in treating diseases of the central nervous system has remained elusive. Here, using an established model...
6.
Kim H, Lee Y, Kwon Y, Kim J
Sci Rep
. 2023 Dec;
13(1):21240.
PMID: 38040919
Brain organoids, which are three-dimensional cell culture models, have the ability to mimic certain structural and functional aspects of the human brain. However, creating these organoids can be a complicated...
7.
Kim J, Hwang Y, Kim S, Chang Y, Kim Y, Kwon Y, et al.
Aging Cell
. 2023 Mar;
22(6):e13825.
PMID: 36964992
Partial cellular reprogramming via transient expression of Oct4, Sox2, Klf4, and c-Myc induces rejuvenation and reduces aged-cell phenotypes. In this study, we found that transcriptional activation of the endogenous Oct4...
8.
Park H, Cho B, Kim H, Saito T, Saido T, Won K, et al.
Nat Commun
. 2023 Feb;
14(1):802.
PMID: 36781874
Alzheimer's disease (AD) is associated with progressive neuronal degeneration as amyloid-beta (Aβ) and tau proteins accumulate in the brain. Glial cells were recently reported to play an important role in...
9.
Kim H, Kim S, Cho B, Shin J, Kim J
Transl Neurodegener
. 2022 Oct;
11(1):45.
PMID: 36284363
Background: The ε4 allele of apolipoprotein E (APOE ε4) is the strongest known genetic risk factor for late-onset Alzheimer's disease (AD), associated with amyloid pathogenesis. However, it is not clear...
10.
Park H, Shin J, Kim Y, Saito T, Saido T, Kim J
Transl Neurodegener
. 2022 Sep;
11(1):41.
PMID: 36109806
Background: Aberrant DNA methylation patterns have been observed in neurodegenerative diseases, including Alzheimer's disease (AD), and dynamic changes in DNA methylation are closely associated with the onset and progression of...