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» Authors » Jonathas Rodrigo Dos Santos

Jonathas Rodrigo Dos Santos

Explore the profile of Jonathas Rodrigo Dos Santos including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 13
Followers 0
Related Specialties
Biochemistry
Neurology
Geriatrics
Top 10 Co-Authors
Luciane Carla Alberici
Carlos Henrique Rocha Catalao
Gustavo Duarte Ferrari
Maria Jose Alves Rocha
Luis Henrique Angenendt da Costa
Anderson Vulczak
Norberto Cysne Coimbra
Elaine Del Bel
Luiz Luciano Falconi-Sobrinho
Luiz G S Branco
Published In
Front Neurol
Biochem J
Antioxidants (Basel)
J Alzheimers Dis
Mol Cell Biochem
Affiliations
Soon will be listed here.
Recent Articles
1.
Fluoxetine mitigates hypothermia and inflammatory responses in lipopolysaccharide-induced systemic inflammation: Insights into serotonergic and hypothalamic thermoregulatory mechanisms
Trajano I, Costa L, Passaglia P, Santos W, Dos Santos J, Alberici L, et al.
Cytokine . 2025 Mar; 189:156909. PMID: 40058091
An abnormally elevated mortality rate is evident in cases of sepsis. To study specific mechanisms of sepsis experimentally, lipopolysaccharide (LPS) systemically administered has been used as a model, in which...
2.
Voluntary wheel running decreases amyloidogenic pathway and rescues cognition and mitochondrial energy metabolism in middle-aged female 3xTg-AD mouse model of Alzheimer's disease
Dos Santos J, Catalao C, Vulczak A, Azzolini A, Alberici L
J Alzheimers Dis . 2024 Nov; 102(2):424-436. PMID: 39573868
Background: Evidence supports the neuroprotective effects of physical activity, either in experimental animal models or humans. However, the biological mechanisms by which physical exercise modulates dementia and Alzheimer's disease (AD)...
3.
Mitigating neuroinflammation in cognitive areas: exploring the impact of HMG-CoA reductase inhibitor
Catalao C, da Costa L, Dos Santos J, Alberici L, Falconi-Sobrinho L, Coimbra N, et al.
Biochem J . 2024 Oct; 481(22):1585-1602. PMID: 39466125
Existing literature suggests that infection-specific mechanisms may play a significant role in the onset and progression of dementia, as opposed to the broader phenomenon of systemic inflammation. In addition, 3-hydroxy-3-methylglutaryl...
4.
Pre-treatment and continuous administration of simvastatin during sepsis improve metabolic parameters and prevent CNS injuries in survivor rats
Catalao C, de Oliveira Souza A, Santos-Junior N, da Costa L, Dos Santos J, Alberici L, et al.
Mol Cell Biochem . 2022 May; 477(11):2657-2667. PMID: 35604517
Sepsis causes overproduction of inflammatory cytokines, organ dysfunction, and cognitive impairment in survivors. In addition to inflammation, metabolic changes occur according to the stage and severity of the disease. Understanding...
5.
One-Week High-Intensity Interval Training Increases Hippocampal Plasticity and Mitochondrial Content without Changes in Redox State
Dos Santos J, Bortolanza M, Ferrari G, Lanfredi G, do Nascimento G, Azzolini A, et al.
Antioxidants (Basel) . 2020 May; 9(5). PMID: 32455608
Evidence suggests that physical exercise has effects on neuronal plasticity as well as overall brain health. This effect has been linked to exercise capacity in modulating the antioxidant status, when...
6.
Energy Metabolism and Redox State in Brains of Wistar Audiogenic Rats, a Genetic Model of Epilepsy
Dechandt C, Ferrari G, Dos Santos J, Cortes de Oliveira J, da Silva-Jr R, Cunha A, et al.
Front Neurol . 2019 Oct; 10:1007. PMID: 31632331
The Wistar Audiogenic Rat (WAR) strain is a genetic model of epilepsy, specifically brainstem-dependent tonic-clonic seizures, triggered by acute auditory stimulation. Chronic audiogenic seizures (audiogenic kindling) mimic temporal lobe epilepsy,...