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Jonathan Spiker

Explore the profile of Jonathan Spiker including associated specialties, affiliations and a list of published articles. Areas
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Citations 14
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Recent Articles
1.
Botsis T, Spiker J, Kreimeyer K, Fatteh M, Wehr J, Najjar M, et al.
Stud Health Technol Inform . 2024 Aug; 316:1854-1855. PMID: 39176852
There is a critical need for a streamlined process to identify genotype-matched individuals eligible for enrollment into clinical trials and/or targeted therapies, as current methodologies face challenges in integrating diverse...
2.
Botsis T, Murray J, Ghanem P, Balan A, Kernagis A, Hardart K, et al.
JCO Clin Cancer Inform . 2023 Apr; 7:e2200108. PMID: 37040583
Purpose: Precision oncology mandates developing standardized common data models (CDMs) to facilitate analyses and enable clinical decision making. Expert-opinion-based precision oncology initiatives are epitomized in Molecular Tumor Boards (MTBs), which...
3.
Kreimeyer K, Spiker J, Botsis T
Stud Health Technol Inform . 2022 Jul; 295:398-401. PMID: 35773895
Many decision support methods and systems in pharmacovigilance are built without explicitly addressing specific challenges that jeopardize their eventual success. We describe two sets of challenges and appropriate strategies to...
4.
Kreimeyer K, Dang O, Spiker J, Munoz M, Rosner G, Ball R, et al.
Comput Biol Med . 2021 Jun; 135:104517. PMID: 34130003
Background: Our objective was to support the automated classification of Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) reports for their usefulness in assessing the possibility of a...
5.
Spiker J, Kreimeyer K, Dang O, Boxwell D, Chan V, Cheng C, et al.
Drug Saf . 2020 May; 43(9):905-915. PMID: 32445187
Introduction: The US FDA receives more than 2 million postmarket reports each year. Safety Evaluators (SEs) review these reports, as well as external information, to identify potential safety signals. With...