Jonathan P Moorman
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Explore the profile of Jonathan P Moorman including associated specialties, affiliations and a list of published articles.
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102
Citations
1690
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Recent Articles
1.
Nguyen L, Pyburn J, Nguyen N, Schank M, Zhao J, Wang L, et al.
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39941145
The interplay between long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) is crucial in the epigenetic regulation of mRNA and protein expression, impacting the development and progression of a plethora of...
2.
Yao Z, Schank M, Zhao J, El Gazzar M, Wang L, Zhang Y, et al.
Front Genome Ed
. 2024 Oct;
6:1467449.
PMID: 39444780
Hepatitis B virus (HBV) infection is a common cause of liver disease worldwide. The current antiviral treatment using nucleotide analogues (NAs) can only suppress HBV replication but cannot eliminate chronic...
3.
Musket A, Davern S, Elam B, Musich P, Moorman J, Jiang Y
Front Nucl Med
. 2024 Oct;
3:1323514.
PMID: 39355029
Radionuclide-mediated diagnosis and therapy have emerged as effective and low-risk approaches to treating breast cancer. Compared to traditional anatomic imaging techniques, diagnostic radionuclide-based molecular imaging systems exhibit much greater sensitivity...
4.
Wang L, Zhao J, Schank M, Hill A, Banik P, Zhang Y, et al.
Front Aging
. 2024 Jun;
5():1414866.
PMID: 38895099
Despite effective control of HIV replication by antiretroviral therapy (ART), a significant number of people living with HIV (PLWH) fail to achieve complete immune reconstitution and thus are deemed immune...
5.
Musket A, Moorman J, Zhang J, Jiang Y
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38731883
The serine-threonine kinase protein kinase A (PKA) is a cyclic AMP (cAMP)-dependent intracellular protein with multiple roles in cellular biology including metabolic and transcription regulation functions. The cAMP-dependent protein kinase...
6.
Wang L, Howell M, Hensley C, Ning K, Moorman J, Yao Z, et al.
J Virol
. 2023 Oct;
97(11):e0095323.
PMID: 37877721
To our knowledge, this is the first report delineating the activation of the master antioxidant defense during EBV latency. We show that EBV-triggered reactive oxygen species production activates the Keap1-NRF2...
7.
Zhang J, Zhang Y, Khanal S, Cao D, Zhao J, Dang X, et al.
J Med Virol
. 2023 Jul;
95(7):e28952.
PMID: 37455550
The presence of hepatitis B virus (HBV) covalently closed circular (ccc) DNA (cccDNA), which serves as a template for viral replication and integration of HBV DNA into the host cell...
8.
Schank M, Zhao J, Wang L, Nguyen L, Zhang Y, Wu X, et al.
Viruses
. 2023 May;
15(5.
PMID: 37243148
We have previously demonstrated mitochondrial dysfunction in aging CD4 T cells from antiretroviral therapy (ART)-controlled people living with HIV (PLWH). However, the underlying mechanisms by which CD4 T cells develop...
9.
Harley J, Pyarajan S, Partan E, Epstein L, Wertheim J, Diwan A, et al.
Open Forum Infect Dis
. 2023 Jan;
9(12):ofac641.
PMID: 36601554
Background: The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has demonstrated the need to share data and biospecimens broadly to optimize clinical...
10.
Dang X, Cao D, Zhao J, Schank M, Khanal S, Nguyen L, et al.
Front Cell Infect Microbiol
. 2022 Nov;
12():1026293.
PMID: 36405960
T cells are crucial for controlling viral infections; however, the mechanisms that dampen their responses during viral infections remain incompletely understood. Here, we studied the role and mechanisms of mitochondrial...