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Jonathan O Dostrovsky

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Articles 86
Citations 2625
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Recent Articles
11.
Wang H, Cao Y, Chiang C, Dostrovsky J, Sessle B
Pain . 2013 Nov; 155(2):429-435. PMID: 24239671
Glial cells are being increasingly implicated in mechanisms underlying pathological pain, and recent studies suggest glial gap junctions involving astrocytes may contribute. The aim of this study was to examine...
12.
Laxton A, Neimat J, Davis K, Womelsdorf T, Hutchison W, Dostrovsky J, et al.
Biol Psychiatry . 2013 Jun; 74(10):714-9. PMID: 23773792
Background: The subcallosal cingulate and adjacent ventromedial prefrontal cortex (collectively referred to here as the subcallosal cortex or SCC) have been identified as key brain areas in emotional processing. The...
13.
Kumar N, Cherkas P, Varathan V, Miyamoto M, Chiang C, Dostrovsky J, et al.
Neurochem Int . 2013 Mar; 62(6):831-5. PMID: 23454190
Pregabalin is effective in treating many neuropathic pain conditions. However, the mechanisms of its analgesic effects remain poorly understood. The aim of the present study was to determine whether pregabalin...
14.
Cao Y, Wang H, Chiang C, Dostrovsky J, Sessle B
J Pain . 2013 Feb; 14(2):193-204. PMID: 23374941
Unlabelled: The aim of this study was to determine whether pregabalin affects nociceptive behavior and central sensitization in a trigeminal neuropathic pain model. A partial infraorbital nerve transection (p-IONX) or...
15.
Kumar N, Cherkas P, Chiang C, Dostrovsky J, Sessle B, Coderre T
Neurochem Int . 2012 Oct; 61(8):1276-9. PMID: 23079194
Our electrophysiological studies have shown that both purinergic and glutamatergic receptors are involved in central sensitization of nociceptive neurons in the medullary dorsal horn (MDH). Here we assessed the effects...
16.
Alavi M, Dostrovsky J, Hodaie M, Lozano A, Hutchison W
Exp Neurol . 2012 Oct; 245:60-71. PMID: 23063495
Parkinson's disease (PD) is accompanied by a significant amount of β-band (11 Hz-30 Hz) neuronal and local field potential (LFP) oscillatory activity in the subthalamic nucleus (STN). Previous studies have...
17.
Cherkas P, Dostrovsky J, Sessle B
Neurosci Lett . 2012 Aug; 526(2):160-3. PMID: 22910609
Central sensitization and purinergic receptor mechanisms have been implicated as important processes in acute and chronic pain conditions following injury or inflammation of peripheral tissues. This study has documented that...
18.
Hazrati L, Wong J, Hamani C, Lozano A, Poon Y, Dostrovsky J, et al.
Mov Disord . 2012 Aug; 27(10):1304-7. PMID: 22865554
Background: Pedunculopontine nucleus (PPN) DBS has emerged as a potential intervention for patients with gait and balance disorders. However, targeting this nucleus can be challenging. We report on the first...
19.
Liu L, Prescott I, Dostrovsky J, Hodaie M, Lozano A, Hutchison W
J Neurophysiol . 2012 Mar; 108(1):5-17. PMID: 22457462
Deep brain stimulation (DBS) in the globus pallidus internus (GPi) has been shown to improve dystonia, a movement disorder of repetitive twisting movements and postures. DBS at frequencies above 60...
20.
Weinberger M, Hutchison W, Alavi M, Hodaie M, Lozano A, Moro E, et al.
Clin Neurophysiol . 2011 Aug; 123(2):358-68. PMID: 21843964
Objective: Deep brain stimulation in the globus pallidus internus (GPi) is used to alleviate the motor symptoms of both Parkinson's disease (PD) and dystonia. We tested the hypothesis that PD...