Jonathan N Townend
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Explore the profile of Jonathan N Townend including associated specialties, affiliations and a list of published articles.
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121
Citations
1733
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Recent Articles
1.
Kwok C, Choy C, Pinney J, Townend J, Whelan C, Fontana M, et al.
ESC Heart Fail
. 2024 Jul;
11(6):3901-3910.
PMID: 39041492
Aims: The efficacy of beta-blockers in cardiac amyloidosis (CA) is unclear, and concerns persist that neurohormonal blockade could worsen symptoms of heart failure. We aimed to assess whether beta-blocker therapy...
2.
Wang K, Balmforth C, Meah M, Daghem M, Moss A, Tzolos E, et al.
J Am Coll Cardiol
. 2024 May;
83(22):2135-2144.
PMID: 38811091
Background: Total coronary atherosclerotic plaque activity across the entire coronary arterial tree is associated with patient-level clinical outcomes. Objectives: We aimed to investigate whether vessel-level coronary atherosclerotic plaque activity is...
3.
Ferro C, Townend J
J Am Coll Cardiol
. 2024 May;
83(24):2437-2439.
PMID: 38739066
No abstract available.
4.
Shakeel I, Sharma H, Hodson J, Iqbal H, Tashfeen R, Ludman P, et al.
J Clin Med
. 2024 Apr;
13(8).
PMID: 38673591
Concomitant atrial fibrillation (AF) is associated with an adverse prognosis in patients with acute myocardial infarction (MI). However, it remains unclear whether this is due to a causal effect of...
5.
Mackenzie I, Hawkey C, Ford I, Greenlaw N, Pigazzani F, Rogers A, et al.
Health Technol Assess
. 2024 Mar;
28(18):1-55.
PMID: 38551218
Background: Allopurinol is a xanthine oxidase inhibitor that lowers serum uric acid and is used to prevent acute gout flares in patients with gout. Observational and small interventional studies have...
6.
Impact of antiplatelet therapy on microvascular thrombosis during ST-elevation myocardial infarction
Khattak S, Townend J, Thomas M
Front Mol Biosci
. 2024 Mar;
11:1287553.
PMID: 38545417
During an acute coronary syndrome, atherosclerotic plaque rupture triggers platelet activation and thrombus formation, which may completely occlude a coronary artery leading to ST-elevation myocardial infarction (STEMI). Although emergency percutaneous...
7.
Edwards N, Ferro C, Townend J
Nephrol Dial Transplant
. 2023 Dec;
39(3):387-394.
PMID: 38061799
The annual American Heart Association (AHA) and National Institutes of Health statistical report details the most up to date statistics related to heart disease, stroke and cardiovascular risk factors, primarily...
8.
Hall C, Law J, Reyat J, Cumberland M, Hang S, Vo N, et al.
Sci Rep
. 2023 Jul;
13(1):12137.
PMID: 37495732
Activation of cardiac fibroblasts and differentiation to myofibroblasts underlies development of pathological cardiac fibrosis, leading to arrhythmias and heart failure. Myofibroblasts are characterised by increased α-smooth muscle actin (α-SMA) fibre...
9.
Edwards N, Price A, Steeds R, Ferro C, Townend J
Nephrol Dial Transplant
. 2023 Jan;
38(8):1798-1806.
PMID: 36690349
The wide overlap between the syndromes of chronic kidney disease (CKD) and chronic heart failure (HF) means that familiarity with the 2021 European Society of Cardiology guidelines is of importance...
10.
Mackenzie I, Hawkey C, Ford I, Greenlaw N, Pigazzani F, Rogers A, et al.
Lancet
. 2022 Oct;
400(10359):1195-1205.
PMID: 36216006
Background: Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to...