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Jonathan M Cordeiro

Explore the profile of Jonathan M Cordeiro including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 1944
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Recent Articles
1.
Owusu-Mensah A, Treat J, Bernardi J, Pfeiffer R, Goodrow R, Tsevi B, et al.
PLoS One . 2024 Jan; 19(1):e0287206. PMID: 38181028
We identified two different inherited mutations in KCNH2 gene, or human ether-a-go-go related gene (hERG), which are linked to Long QT Syndrome. The first mutation was in a 1-day-old infant,...
2.
Calloe K, Geryk M, Freude K, Treat J, Vold V, Frederiksen H, et al.
Europace . 2022 Jun; 24(12):2015-2027. PMID: 35726875
Aims: Variants in SCN5A encoding Nav1.5 are associated with cardiac arrhythmias. We aimed to determine the mechanism by which c.638G>A in SCNA5 resulting in p.Gly213Asp (G213D) in Nav1.5 altered Na+...
3.
Treat J, Pfeiffer R, Barajas-Martinez H, Goodrow R, Bot C, Haedo R, et al.
Int J Mol Sci . 2021 Jul; 22(13). PMID: 34281161
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are used for genetic models of cardiac diseases. We report an arrhythmia syndrome consisting of Early Repolarization Syndrome (ERS) and Short QT Syndrome...
4.
Akwaboah A, Tsevi B, Yamlome P, Treat J, Brucal-Hallare M, Cordeiro J, et al.
Front Physiol . 2021 Jul; 12:675867. PMID: 34220540
The formulation of biophysical models generally requires optimization strategies for reproducing experimentally observed phenomena. In electrophysiological modeling, robust nonlinear regressive methods are often crucial for guaranteeing high fidelity models. Human...
5.
Deo M, Akwaboah A, Tsevi B, Treat J, Cordeiro J
Arch Stem Cell Ther . 2021 Feb; 1(1):14-18. PMID: 33604593
No abstract available.
6.
Pathmanathan P, Galappaththige S, Cordeiro J, Kaboudian A, Fenton F, Gray R
Front Physiol . 2020 Dec; 11:585400. PMID: 33329034
Computational modeling of cardiac electrophysiology (EP) has recently transitioned from a scientific research tool to clinical applications. To ensure reliability of clinical or regulatory decisions made using cardiac EP models,...
7.
Akwaboah A, Yamlome P, Treat J, Cordeiro J, Deo M
Annu Int Conf IEEE Eng Med Biol Soc . 2020 Oct; 2020:2463-2466. PMID: 33018505
Modeling cardiac cell electrophysiology relies on fitting model equations to experimental data obtained under voltage/current clamping conditions. The fitting procedure for these often-nonlinear ionic current equations are mostly executed by...
8.
Barajas-Martinez H, Smith M, Hu D, Goodrow R, Puleo C, Hasdemir C, et al.
Stem Cells Int . 2020 Sep; 2020:8842398. PMID: 32952569
Background: We report an inherited cardiac arrhythmia syndrome consisting of Brugada and Early Repolarization Syndrome associated with variants in , , and . The proband inherited the 3 mutations and...
9.
Gussak G, Marszalec W, Yoo S, Modi R, OCallaghan C, Aistrup G, et al.
Circ Arrhythm Electrophysiol . 2020 May; 13(6):e008179. PMID: 32433891
Background: We have identified a novel form of abnormal Ca wave activity in normal and failing dog atrial myocytes which occurs during the action potential (AP) and is absent during...
10.
Treat J, Goodrow R, Bot C, Haedo R, Cordeiro J
Biochem Pharmacol . 2019 Aug; 169:113608. PMID: 31465775
Background: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are used for many applications including safety pharmacology. However, a deficiency or complete absence of several K currents suggests repolarization reserve is...