Jonathan L Katz
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Explore the profile of Jonathan L Katz including associated specialties, affiliations and a list of published articles.
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112
Citations
2318
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Recent Articles
1.
Hiranita T, Soto P, Katz J
J Pharmacol Exp Ther
. 2024 Oct;
391(3):415-429.
PMID: 39443142
Previous studies indicated differing effects of dopamine D-like and D-like receptor (DR and DR, respectively) agonists on cocaine self-administration. Leftward shifts by DR agonists in the cocaine self-administration dose-effect function...
2.
Hiranita T, Li S, Katz J
J Pharmacol Exp Ther
. 2024 Aug;
391(2):308-316.
PMID: 39179413
Previous studies demonstrated that sigma receptor (R) antagonists alone fail to alter cocaine self-administration despite blocking various other effects of cocaine. However, R antagonists when combined with dopamine transporter (DAT)...
3.
Hersey M, Mereu M, Jones C, Bartole M, Chen A, Cao J, et al.
Eur J Neurosci
. 2024 Mar;
59(10):2436-2449.
PMID: 38444104
Psychostimulant use disorders (PSUD) are prevalent; however, no FDA-approved medications have been made available for treatment. Previous studies have shown that dual inhibitors of the dopamine transporter (DAT) and sigma...
4.
Li F, Kopajtic T, Katz J, Luo D, Prisinzano T, Imler G, et al.
Molecules
. 2022 Dec;
27(24).
PMID: 36557961
The design of enantiopure stereoisomers of N-2-phenylcyclopropylmethyl-substituted ortho-c oxide-bridged phenylmorphans, the E and Z isomers of an N-cinnamyl moiety, and N-propyl enantiomers were based on combining the most potent oxide-bridged...
5.
Yue K, Katz J, Shu X
Psychopharmacology (Berl)
. 2022 Feb;
239(3):897-908.
PMID: 35107609
The potential of mitragynine to produce physiological dependence (withdrawal) was assessed using a rapid assessment procedure with male ICR mice exposed to heroin-admixed food followed by naloxone (subcutaneously, s.c.) precipitation...
6.
Intagliata S, Agha H, Kopajtic T, Katz J, Kamble S, Sharma A, et al.
Med Chem Res
. 2021 Feb;
29(9):1697-1706.
PMID: 33584084
In this work we report the structure-activity relationships, binding properties, and metabolic stability studies of a series of benzo[]thiazol-2(3)one as sigma receptors (σRs) ligands. Specifically, to improve the metabolic stability...
7.
Wang M, Irvin T, Herdman C, Hanna R, Hassan S, Lee Y, et al.
Molecules
. 2020 Jun;
25(11).
PMID: 32517185
(-)--Phenethyl analogs of optically pure -norhydromorphone were synthesized and pharmacologically evaluated in several in vitro assays (opioid receptor binding, stimulation of [S]GTPγS binding, forskolin-induced cAMP accumulation assay, and MOR-mediated β-arrestin...
8.
Mereu M, Hiranita T, Jordan C, Chun L, Lopez J, Coggiano M, et al.
Neuropsychopharmacology
. 2020 Apr;
45(9):1518-1526.
PMID: 32340023
Modafinil and methylphenidate are medications that inhibit the neuronal reuptake of dopamine, a mechanism shared with cocaine. Their use as "smart drugs" by healthy subjects poses health concerns and requires...
9.
Job M, Katz J
Psychopharmacology (Berl)
. 2019 Aug;
236(12):3601-3612.
PMID: 31399853
Rationale And Objectives: Rimcazole, a σ-receptor antagonist with affinity for the dopamine transporter (DAT), decreases rates of cocaine self-administration at doses lower than those that affect food-reinforced responding. As response...
10.
Yue K, Tanda G, Katz J, Zanettini C
Behav Pharmacol
. 2019 Feb;
31(2&3):186-195.
PMID: 30741729
The Toll-like receptor 4 (TLR4) antagonists, (+)-naloxone and (+)-naltrexone, have been reported to decrease self-administration of opioids in rats and to reduce other preclinical indicators of abuse potential. However, under...