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Jonathan Karpelowsky

Explore the profile of Jonathan Karpelowsky including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 283
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Recent Articles
1.
Sullivan E, Thiruthaneeswaran N, Karpelowsky J, Busuttil G, Flower E, Bucci J, et al.
J Med Imaging Radiat Oncol . 2024 Oct; PMID: 39440696
Introduction: Paediatric cancers are rare, and most children requiring radiation therapy receive external beam radiation (EBRT). Although EBRT may offer organ preservation compared to surgery, it can be associated with...
2.
Riehle K, Vasudevan S, Bondoc A, Cuenca A, Garnier H, Kastenberg Z, et al.
Pediatr Blood Cancer . 2024 Jul; :e31155. PMID: 38953150
Two percent of pediatric malignancies arise primarily in the liver; roughly 60% of these cancers are hepatoblastoma (HB). Despite the rarity of these cases, international collaborative efforts have led to...
3.
Adams S, Perera M, Fung S, Maxton J, Karpelowsky J
ANZ J Surg . 2024 Jun; 94(9):1569-1577. PMID: 38873960
Background: Appendicitis is the commonest paediatric surgical emergency. Adult studies suggest non-operative management (NOM) may have a place in care. There have been no adequately powered randomized controlled trials in...
4.
Daly R, Hetherington K, Wadling B, Jacobs C, Karpelowsky J, Wakefield C
Cancer Med . 2024 May; 13(9):e7209. PMID: 38716651
Objective: Precision medicine is transforming cancer treatment, yet the perspectives of surgeons who often play a critical role in the delivery of precision medicine remain understudied. Methods: We conducted semi-structured...
5.
Kahana-Edwin S, Torpy J, Cain L, Mullins A, McCowage G, Woodfield S, et al.
Cancers (Basel) . 2024 Jan; 16(1). PMID: 38201440
Hepatoblastoma is characterized by driver mutations in , making it an attractive biomarker for a liquid biopsy approach utilizing circulating tumor DNA (ctDNA). This prospective observational study sought to ascertain...
6.
Kastenberg Z, Baertschiger R, Cuenca A, Galvan N, Lemoine C, Roach J, et al.
Semin Pediatr Surg . 2023 Nov; 32(5):151340. PMID: 38008042
The appropriate management of pediatric liver malignancies, primarily hepatoblastoma and hepatocellular carcinoma, requires an in depth understanding of contemporary preoperative risk stratification, experience with advanced hepatobiliary surgery, and a good...
7.
Grebstad Tune B, Sareen H, Powter B, Kahana-Edwin S, Cooper A, Koh E, et al.
Biomedicines . 2023 Nov; 11(11). PMID: 38001908
Genetic histone variants have been implicated in cancer development and progression. Mutations affecting the histone 3 (H3) family, H3.1 (encoded by and ) and H3.3 (encoded by ), are mainly...
8.
Daly R, Hetherington K, Hazell E, Wadling B, Tyrrell V, Tucker K, et al.
J Pers Med . 2023 Jul; 13(7). PMID: 37511646
Precision medicine programs aim to utilize novel technologies to identify personalized treatments for children with cancer. Delivering these programs requires interdisciplinary efforts, yet the many groups involved are understudied. This...
9.
Soundappan S, Lam A, Lam L, Cass D, Holland A, Karpelowsky J
POCUS J . 2023 Mar; 6(1):33-35. PMID: 36895503
To study the diagnostic accuracy of surgeon performed ultrasound (SPU) in the diagnosis of children presenting with clinical suspicion of intussusception to a tertiary paediatric facility in NSW, Australia. Children...
10.
Abdelhafeez A, Reljic T, Kumar A, Banu T, Cox S, Davidoff A, et al.
Pediatr Blood Cancer . 2022 Aug; 69(12):e29906. PMID: 35929184
Background: Survival of Wilms tumor (WT) is > 90% in high-resource settings but < 30% in low-resource settings. Adapting a standardized surgical approach to WT is challenging in low-resource settings,...