Jonathan K Y Lai
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Explore the profile of Jonathan K Y Lai including associated specialties, affiliations and a list of published articles.
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9
Citations
261
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Recent Articles
1.
Asbury S, Lai J, Rilett K, Haqqee Z, Darwin B, Ellegood J, et al.
Behav Brain Funct
. 2025 Jan;
21(1):1.
PMID: 39748372
Gene-environment interactions in the postnatal period have a long-term impact on neurodevelopment. To effectively assess neurodevelopment in the mouse, we developed a behavioural pipeline that incorporates several validated behavioural tests...
2.
Francella C, Green M, Caspani G, Lai J, Rilett K, Foster J
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499393
Decades of research have established the role of microbiota-brain communication in behaviour and brain function. Studies have shown that microbiota composition and diversity are influenced by a variety of factors...
3.
Weiss J, Lai J, Lee V, Lunsky Y
Autism Res
. 2020 Sep;
14(2):324-332.
PMID: 32902130
Transitioning into adulthood is fraught with challenges for autistic youth. A greater understanding of the facilitators of community involvement in school and employment during this period is warranted. The current...
4.
Aujnarain A, Luo O, Taylor N, Lai J, Foster J
Behav Brain Res
. 2018 Jan;
342:43-50.
PMID: 29339005
A host of scholarly work has characterized the positive effects of exercise and environmental enrichment on behaviour and cognition in animal studies. The purpose of this study was to investigate...
5.
Priority service needs and receipt across the lifespan for individuals with autism spectrum disorder
Lai J, Weiss J
Autism Res
. 2017 Apr;
10(8):1436-1447.
PMID: 28383156
Individuals with Autism Spectrum Disorder (ASD) have a range of health, community, and social support needs across the lifespan that create age-specific challenges in navigating service sectors. In this study,...
6.
Lai J, Doering L, Foster J
J Comp Neurol
. 2015 Aug;
524(4):807-28.
PMID: 26235839
Neuroligins and neurexins are transsynaptic proteins involved in the maturation of glutamatergic and GABAergic synapses. Research has identified synaptic proteins and function as primary contributors to the development of fragile...
7.
Lai J, Sobala-Drozdowski M, Zhou L, Doering L, Faure P, Foster J
Behav Brain Res
. 2013 Nov;
259:119-30.
PMID: 24211451
The fmr1 knock out (KO) mouse has been a useful animal model to understand pathology and treatment of FXS, both anatomically and behaviorally. Ultrasonic vocalizations (USVs) are a behavioral tool...
8.
Roullet F, Lai J, Foster J
Neurotoxicol Teratol
. 2013 Feb;
36:47-56.
PMID: 23395807
Valproic acid (VPA) is both an anti-convulsant and a mood stabilizer. Clinical studies over the past 40 years have shown that exposure to VPA in utero is associated with birth...
9.
Wilcox J, Lai J, Semple E, Brisson B, Gartley C, Armstrong J, et al.
PLoS One
. 2011 May;
6(5):e19768.
PMID: 21611190
Pluripotent stem cell lines have been generated in several domestic animal species; however, these lines traditionally show poor self-renewal and differentiation. Using canine embryonic stem cell (cESC) lines previously shown...