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Jonathan J Wong

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Articles 13
Citations 101
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Recent Articles
1.
Davis J, Jayathilake B, Chandrasekaran S, Wong J, Deotte J, Baker S, et al.
Sci Rep . 2024 Sep; 14(1):22662. PMID: 39349533
Recent advances in 3D printing have enabled the manufacture of porous electrodes which cannot be machined using traditional methods. With micron-scale precision, the pore structure of an electrode can now...
2.
Bergman Z, Wong J, Drubin D, Barnes G
J Cell Sci . 2023 Jun; 136(11). PMID: 37305999
The budding yeast Saccharomyces cerevisiae has a closed mitosis in which the mitotic spindle and the cytoplasmic microtubules (MTs), both of which generate forces to faithfully segregate chromosomes, remain separated...
3.
Nistanaki S, Williams C, Wigman B, Wong J, Haas B, Popov S, et al.
Science . 2022 Dec; 378(6624):1085-1091. PMID: 36480623
From the preparation of pharmaceuticals to enzymatic construction of natural products, carbocations are central to molecular synthesis. Although these reactive intermediates are engaged in stereoselective processes in nature, exerting enantiocontrol...
4.
Fan Z, Chen X, Tanaka K, Park H, Lam N, Wong J, et al.
Nature . 2022 Aug; 610(7930):87-93. PMID: 35944562
Direct molecular editing of heteroarene carbon-hydrogen (C-H) bonds through consecutive selective C-H functionalization has the potential to grant rapid access into diverse chemical spaces, which is a valuable but often...
5.
Huffman B, Chu T, Hanaki Y, Wong J, Chen S, Houk K, et al.
Angew Chem Int Ed Engl . 2021 Nov; 61(3):e202114514. PMID: 34820990
A strategy to control the diastereoselectivity of bond formation at a prochiral attached-ring bridgehead is reported. An unusual stereodivergent Michael reaction relies on basic vs. Lewis acidic conditions and non-covalent...
6.
Provencher P, Hoskin J, Wong J, Chen X, Yu J, Houk K, et al.
J Am Chem Soc . 2021 Nov; 143(48):20035-20041. PMID: 34817163
Methylene-selective C-H functionalization is a significant hurdle that remains to be addressed in the field of Pd(II) catalysis. We report a Pd(II)-catalyzed synthesis of benzocyclobutenes by methylene-selective C(sp)-H arylation of...
7.
Hou B, Wong J, Lv N, Wang Y, Houk K, Li C
Nat Commun . 2021 Sep; 12(1):5239. PMID: 34475378
Bridged medium-sized bicyclo[m.n.2] ring systems are common in natural products and potent pharmaceuticals, and pose a great synthetic challenge. Chemistry for making bicyclo[m.n.2] ring systems remains underdeveloped. Currently, there are...
8.
Wang D, Chen X, Wong J, Jin L, Li M, Zhao Y, et al.
Nat Commun . 2021 Jan; 12(1):524. PMID: 33483484
Heteroarenes containing carbon-silicon (C-Si) bonds are important building blocks that play an important role in the construction of natural products, pharmaceuticals, and organic materials. In this context, the C-H silylation...
9.
Wang Z, Chen X, Wu L, Wong J, Liang Y, Zhao Y, et al.
Angew Chem Int Ed Engl . 2021 Jan; 60(15):8500-8504. PMID: 33449421
Robust strategies to enable the rapid construction of complex organoboronates in selective, practical, low-cost, and environmentally friendly modes remain conspicuously underdeveloped. Here, we develop a general strategy for the site-selective...
10.
Xu Y, Wong J, Samkian A, Ko J, Chen S, Houk K, et al.
J Am Chem Soc . 2020 Dec; 142(50):20987-20993. PMID: 33275423
The efficient -selective cross-metathesis between acrylamides and common terminal olefins has been developed by the use of novel cyclometalated ruthenium catalysts with bulky N-heterocyclic carbene (NHC) ligands. Superior reactivity and...