Jonathan J Wilksch
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Explore the profile of Jonathan J Wilksch including associated specialties, affiliations and a list of published articles.
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25
Citations
586
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Recent Articles
1.
Yan S, Cheng G, Yang Z, Guo Y, Chen L, Fu Y, et al.
Biotechnol Adv
. 2024 Dec;
79:108507.
PMID: 39708988
Terahertz (THz) radiation is widely recognized as a non-destructive, label-free, and highly- sensitive tool for biomedical detections. Nevertheless, its application in precision biomedical fields faces challenges due to poor spatial...
2.
Terahertz label-free detection of nicotine-induced neural cell changes and the underlying mechanisms
Tang M, Zhang M, Fu Y, Chen L, Li D, Zhang H, et al.
Biosens Bioelectron
. 2023 Sep;
241:115697.
PMID: 37751650
Nicotine exposure can lead to neurological impairments and brain tumors, and a label-free and nondestructive detection technique is urgently required by the scientific community to assess the effects of nicotine...
3.
Singh S, Wilksch J, Dunstan R, Mularski A, Wang N, Hocking D, et al.
Microbiol Spectr
. 2022 Aug;
10(4):e0151721.
PMID: 35913154
Despite the importance of encapsulation in bacterial pathogenesis, the biochemical mechanisms and forces that underpin retention of capsule by encapsulated bacteria are poorly understood. In Gram-negative bacteria, there may be...
4.
Dunstan R, Bamert R, Belousoff M, Short F, Barlow C, Pickard D, et al.
Microbiol Spectr
. 2021 Aug;
9(1):e0102321.
PMID: 34431721
The production of capsular polysaccharides by Klebsiella pneumoniae protects the bacterial cell from harmful environmental factors such as antimicrobial compounds and infection by bacteriophages (phages). To bypass this protective barrier,...
5.
Thung T, White M, Dai W, Wilksch J, Bamert R, Rocker A, et al.
mSystems
. 2021 May;
6(3):e0024221.
PMID: 34042467
Antimicrobial resistance (AMR) continues to evolve as a major threat to human health, and new strategies are required for the treatment of AMR infections. Bacteriophages (phages) that kill bacterial pathogens...
6.
Zhang H, Wang H, Wilksch J, Strugnell R, Gee M, Feng X
Soft Matter
. 2021 Feb;
17(8):2042-2049.
PMID: 33592087
Turgor pressure and envelope elasticity of bacterial cells are two mechanical parameters that play a dominant role in cellular deformation, division, and motility. However, a clear understanding of these two...
7.
Rocker A, Lacey J, Belousoff M, Wilksch J, Strugnell R, Davies M, et al.
mBio
. 2020 Apr;
11(2).
PMID: 32291303
In Gram-negative bacteria, the permeability of the outer membrane governs rates of antibiotic uptake and thus the efficacy of antimicrobial treatment. Hydrophilic drugs like β-lactam antibiotics depend on diffusion through...
8.
Chen L, Wilksch J, Liu H, Zhang X, Torres V, Bi W, et al.
J Med Microbiol
. 2020 Apr;
69(3):402-413.
PMID: 32223838
Autoinducer-2 (AI-2) quorum sensing is a bacterial communication system that responds to cell density. The system requires activity to produce AI-2, which can regulate gene expression and processes such as...
9.
Husna A, Wang N, Wilksch J, Newton H, Hocking D, Hay I, et al.
Biochem J
. 2019 Nov;
476(22):3435-3453.
PMID: 31675053
Key physiological differences between bacterial and mammalian metabolism provide opportunities for the development of novel antimicrobials. We examined the role of the multifunctional enzyme S-adenosylhomocysteine/Methylthioadenosine (SAH/MTA) nucleosidase (Pfs) in the...
10.
Grinter R, Hay I, Song J, Wang J, Teng D, Dhanesakaran V, et al.
PLoS Biol
. 2018 Aug;
16(8):e2006026.
PMID: 30071011
Iron is essential for life. Accessing iron from the environment can be a limiting factor that determines success in a given environmental niche. For bacteria, access of chelated iron from...