Jonathan J Halford
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Explore the profile of Jonathan J Halford including associated specialties, affiliations and a list of published articles.
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63
Citations
980
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Recent Articles
11.
Tatum W, Mani J, Jin K, Halford J, Gloss D, Fahoum F, et al.
Clin Neurophysiol
. 2021 Dec;
134:111-128.
PMID: 34955428
The objective of this clinical practice guideline is to provide recommendations on the indications and minimum standards for inpatient long-term video-electroencephalographic monitoring (LTVEM). The Working Group of the International League...
12.
Tatum W, Mani J, Jin K, Halford J, Gloss D, Fahoum F, et al.
Epilepsia
. 2021 Dec;
63(2):290-315.
PMID: 34897662
The objective of this clinical practice guideline is to provide recommendations on the indications and minimum standards for inpatient long-term video-electroencephalographic monitoring (LTVEM). The Working Group of the International League...
13.
Sander J, Rosenfeld W, Halford J, Steinhoff B, Biton V, Toledo M
Epilepsia
. 2021 Nov;
63(1):139-149.
PMID: 34813673
Objective: We determined retention on open-label cenobamate therapy in the clinical development program to assess the long-term efficacy and tolerability of adjunctive cenobamate in individuals with uncontrolled focal seizures. Methods:...
14.
French J, Cole A, Faught E, Theodore W, Vezzani A, Liow K, et al.
Neurology
. 2021 Sep;
97(18):e1757-e1767.
PMID: 34521687
Background And Objectives: To explore efficacy/safety of natalizumab, a humanized monoclonal anti-α4-integrin antibody, as adjunctive therapy in adults with drug-resistant focal epilepsy. Methods: Participants with ≥6 seizures during the 6-week...
15.
Scheffer I, Halford J, Miller I, Nabbout R, Sanchez-Carpintero R, Shiloh-Malawsky Y, et al.
Epilepsia
. 2021 Aug;
62(10):2505-2517.
PMID: 34406656
Objective: Add-on cannabidiol (CBD) reduced seizures associated with Dravet syndrome (DS) in two randomized, double-blind, placebo-controlled trials: GWPCARE1 Part B (NCT02091375) and GWPCARE2 (NCT02224703). Patients who completed GWPCARE1 Part A...
16.
Patel A, Mazurkiewicz-Beldzinska M, Chin R, Gil-Nagel A, Gunning B, Halford J, et al.
Epilepsia
. 2021 Jul;
62(9):2228-2239.
PMID: 34287833
Objective: Lennox-Gastaut syndrome (LGS) is an epileptic encephalopathy that is often treatment resistant. Efficacy and safety of add-on cannabidiol (CBD) to treat seizures associated with LGS was demonstrated in two...
17.
Halford J, Sperling M, Arkilo D, Asgharnejad M, Zinger C, Xu R, et al.
Epilepsy Res
. 2021 May;
174:106646.
PMID: 33940389
Objective: To evaluate the safety, tolerability, and pharmacokinetics of soticlestat, a first-in-class cholesterol 24-hydroxylase inhibitor, in adults with developmental and/or epileptic encephalopathies (DEE). Methods: The study comprised a 30-day, randomized,...
18.
Halford J, Clunie D, Brinkmann B, Krefting D, Remi J, Rosenow F, et al.
Clin Neurophysiol
. 2021 Mar;
132(4):993-997.
PMID: 33662849
A standard format for neurophysiology data is urgently needed to improve clinical care and promote research data exchange. Previous neurophysiology format standardization projects have provided valuable insights into how to...
19.
Ge W, Jing J, An S, Herlopian A, Ng M, Struck A, et al.
J Neurosci Methods
. 2020 Nov;
351:108966.
PMID: 33131680
Objectives: Seizures and seizure-like electroencephalography (EEG) patterns, collectively referred to as "ictal interictal injury continuum" (IIIC) patterns, are commonly encountered in critically ill patients. Automated detection is important for patient...
20.
Thomas J, Jin J, Thangavel P, Bagheri E, Yuvaraj R, Dauwels J, et al.
Int J Neural Syst
. 2020 Aug;
30(11):2050030.
PMID: 32812468
Visual evaluation of electroencephalogram (EEG) for Interictal Epileptiform Discharges (IEDs) as distinctive biomarkers of epilepsy has various limitations, including time-consuming reviews, steep learning curves, interobserver variability, and the need for...