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Jonathan G Leung

Explore the profile of Jonathan G Leung including associated specialties, affiliations and a list of published articles. Areas
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Articles 87
Citations 479
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Recent Articles
1.
Gannon J, Chengappa K, Cotes R, Leung J, Frailey P, Piechowicz M, et al.
Ment Health Clin . 2025 Feb; 15(1):30-35. PMID: 39974758
Clozapine is the only medication approved for treatment-resistant schizophrenia. Clozapine toxicity associated with COVID-19 infection could be amplified by concomitant nirmatrelvir/ritonavir. Knowledge gaps among clinicians and patients led to patient...
2.
Ercis M, Cole K, Dierkhising R, Ozerdem A, Markota M, Singh B, et al.
J Clin Psychopharmacol . 2025 Jan; 45(2):85-91. PMID: 39804782
Background: Clozapine is effective for treatment-resistant schizophrenia and bipolar disorder but is often discontinued due to adverse effects. This study compared early clozapine discontinuation rates and reasons in patients with...
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Elmaghraby R, Pines A, Geske J, Coombes B, Leung J, Croarkin P, et al.
JAACAP Open . 2024 Nov; 2(2):135-144. PMID: 39554204
Objective: Epidemiological studies suggest that patients with attention-deficit/hyperactivity disorder (ADHD) treated with amphetamines have an increased risk of newly diagnosed psychosis. This risk in youth is poorly understood. This investigation...
5.
Markota M, Morgan 3rd R, Leung J
Schizophrenia (Heidelb) . 2024 Sep; 10(1):74. PMID: 39223138
No abstract available.
6.
Markota M, Croarkin P, Coombes B, Gentry M, Leung J
Schizophr Res . 2024 Aug; 272:77-78. PMID: 39197319
No abstract available.
7.
Kummerlowe M, Leung J, Kummer L, Moore K, Huppert R, Betcher H
Breastfeed Med . 2024 Aug; 19(10):796-800. PMID: 39109411
Lithium remains a gold standard treatment for bipolar disorder including during peripartum. Historically, guidelines advised against breastfeeding while taking lithium though recent data suggest it is acceptable for a healthy...
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Leung J, Bye K, Leloux M, Markota M, Allen N
Ther Drug Monit . 2024 Jun; PMID: 38842546
No abstract available.
9.
Nuebel M, Leung J, Hughes C, McGrane I
Ment Health Clin . 2024 Jun; 14(3):204-211. PMID: 38835819
Introduction: Clozapine is the only antipsychotic approved for treatment-resistant schizophrenia, but without appropriate monitoring, it can be associated with potentially fatal outcomes. An International Adult Clozapine Titration Guideline categorizes patients...
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Kuhn A, Determan M, Wright J, Matey E, Leung J
Ment Health Clin . 2024 Jun; 14(3):220-223. PMID: 38835816
Clozapine is primarily metabolized via cytochrome P450(CYP)1A2 and to a lesser extent CYP3A4, CYP2C19, and CYP2D6. Metabolic inhibitors of clozapine, such as fluvoxamine and ciprofloxacin, are important to recognize to...