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Jonathan Digby-Bell

Explore the profile of Jonathan Digby-Bell including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 327
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Recent Articles
1.
Zhao J, Stacey D, Eriksson N, Macdonald-Dunlop E, Hedman A, Kalnapenkis A, et al.
Nat Immunol . 2023 Sep; 24(11):1960. PMID: 37679551
No abstract available.
2.
Zhao J, Stacey D, Eriksson N, Macdonald-Dunlop E, Hedman A, Kalnapenkis A, et al.
Nat Immunol . 2023 Aug; 24(9):1540-1551. PMID: 37563310
Circulating proteins have important functions in inflammation and a broad range of diseases. To identify genetic influences on inflammation-related proteins, we conducted a genome-wide protein quantitative trait locus (pQTL) study...
3.
Pavlidis P, Tsakmaki A, Pantazi E, Li K, Cozzetto D, Digby-Bell J, et al.
Nat Commun . 2022 Oct; 13(1):5820. PMID: 36192482
The function of interleukin-22 (IL-22) in intestinal barrier homeostasis remains controversial. Here, we map the transcriptional landscape regulated by IL-22 in human colonic epithelial organoids and evaluate the biological, functional...
4.
Ardalan Z, Con D, Chandran S, Digby-Bell J, Gibson D, Pham A, et al.
J Crohns Colitis . 2021 Jul; 16(1):18-26. PMID: 34302731
Background And Aims: Currently used endoscopic items for the assessment of pouchitis and cuffitis have deficiencies in reliability and validation. We assessed the reliability and accuracy of new endoscopic items...
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Ibraheim H, Samaan M, Srinivasan A, Brain O, Digby-Bell J, Irving P, et al.
Ann Gastroenterol . 2020 Mar; 33(2):170-177. PMID: 32127738
Background: The GEMINI trials established the efficacy of vedolizumab in moderate-to-severe inflammatory bowel disease (IBD) and demonstrated a favorable safety profile, suggesting it may be advantageous in older patients at...
7.
Powell N, Pantazi E, Pavlidis P, Tsakmaki A, Li K, Yang F, et al.
Gut . 2019 Dec; 69(3):578-590. PMID: 31792136
Objective: The functional role of interleukin-22 (IL22) in chronic inflammation is controversial, and mechanistic insights into how it regulates target tissue are lacking. In this study, we evaluated the functional...
8.
Samaan M, Pavlidis P, Digby-Bell J, Johnston E, Dhillon A, Paramsothy R, et al.
Frontline Gastroenterol . 2018 Jul; 9(3):221-231. PMID: 30047549
Objective: To gain an understanding of the effectiveness of golimumab in a 'real-world' setting. Design: Retrospective cohort study using prospectively maintained clinical records. Setting: Two UK tertiary IBD centres. Patients:...
9.
Digby-Bell J, Williams A, Irving P, Goldenberg S
BMJ Case Rep . 2018 Mar; 2018. PMID: 29507020
We present the first reported case of successful treatment of recurrent infection with faecal microbiota transplantation delivered antegrade with a colonoscope through a diverting ileostomy.
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Digby-Bell J, Zeki S
BMJ Case Rep . 2017 Dec; 2017. PMID: 29269361
Uvular necrosis is an extremely rare complication of gastroscopy. We describe the fifth published case of uvular necrosis following an uncomplicated diagnostic gastroscopy in a young man. Presentation with severe...