Jonathan D Charlesworth
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Explore the profile of Jonathan D Charlesworth including associated specialties, affiliations and a list of published articles.
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13
Citations
268
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Recent Articles
1.
Singh H, Baker F, Ojile J, Adlou B, Kolotovska V, Rigot S, et al.
Sleep Med
. 2024 Aug;
122:141-148.
PMID: 39173210
Objective/background: There is a significant unmet need for safe and effective nonpharmacological therapies for restless legs syndrome (RLS). The objective was to evaluate the efficacy and safety of tonic motor...
2.
Koparkar A, Warren T, Charlesworth J, Shin S, Brainard M, Veit L
Elife
. 2024 Apr;
13.
PMID: 38635312
Complex skills like speech and dance are composed of ordered sequences of simpler elements, but the neuronal basis for the syntactic ordering of actions is poorly understood. Birdsong is a...
3.
Buchfuhrer M, Roy A, Rodriguez S, Charlesworth J
BMC Neurol
. 2023 Nov;
23(1):415.
PMID: 37990163
Background: There is a large population of restless legs syndrome (RLS) patients who are refractory to medication. Whereas experts recommend off-label opioids as an effective long-term treatment for refractory RLS,...
4.
Bogan R, Roy A, Kram J, Ojile J, Rosenberg R, Hudson J, et al.
Sleep
. 2023 Jul;
46(10).
PMID: 37458698
Study Objectives: The purpose of this study was to evaluate the efficacy and safety/tolerability of bilateral high-frequency tonic motor activation (TOMAC) in patients with medication-refractory restless legs syndrome (RLS). Methods:...
5.
Roy A, Ojile J, Kram J, Olin J, Rosenberg R, Hudson J, et al.
Sleep
. 2023 Jul;
46(10).
PMID: 37439365
Study Objectives: To evaluate long-term efficacy and safety of tonic motor activation (TOMAC) for treatment of medication-refractory moderate-to-severe primary restless legs syndrome (RLS). Methods: In the parent study (RESTFUL), adults...
6.
Charlesworth J, Adlou B, Singh H, Buchfuhrer M
J Clin Sleep Med
. 2023 Mar;
19(7):1199-1209.
PMID: 36856064
Study Objectives: Restless legs syndrome (RLS) is a prevalent sleep disorder with limited treatment options. Bilateral high-frequency noninvasive peroneal nerve stimulation (NPNS) reduces RLS symptoms. Here, we sought to characterize...
7.
Buchfuhrer M, Baker F, Singh H, Kolotovska V, Adlou B, Anand H, et al.
J Clin Sleep Med
. 2021 May;
17(8):1685-1694.
PMID: 33949942
Study Objectives: Restless legs syndrome (RLS) is a common neurological disorder characterized by an uncontrollable nocturnal urge to move the legs and often associated with chronic sleep disturbances. The most...
8.
Tyler W, Boasso A, Mortimore H, Silva R, Charlesworth J, Marlin M, et al.
Sci Rep
. 2015 Sep;
5:13865.
PMID: 26353920
We engineered a transdermal neuromodulation approach that targets peripheral (cranial and spinal) nerves and utilizes their afferent pathways as signaling conduits to influence brain function. We investigated the effects of...
9.
Warren T, Charlesworth J, Tumer E, Brainard M
J Neurosci
. 2012 Nov;
32(44):15414-25.
PMID: 23115179
Variation in sequencing of actions occurs in many natural behaviors, yet how such variation is maintained is poorly understood. We investigated maintenance of sequence variation in adult Bengalese finch song,...
10.
Charlesworth J, Warren T, Brainard M
Nature
. 2012 Jun;
486(7402):251-5.
PMID: 22699618
We learn complex skills such as speech and dance through a gradual process of trial and error. Cortical-basal ganglia circuits have an important yet unresolved function in this trial-and-error skill...