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Jonathan Alfred Fletcher

Explore the profile of Jonathan Alfred Fletcher including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Hsueh Y, Chang H, Shan Y, Sun H, Fletcher J, Li C, et al.
Oncogene . 2019 Aug; 38(38):6550-6565. PMID: 31363162
Gastrointestinal stromal tumors (GISTs) are frequently driven by auto-activated, mutant KIT and have durable response to KIT tyrosine kinase inhibitor. However, acquired resistance is an increasing clinical issue in GIST...
2.
Falkenhorst J, Grunewald S, Muhlenberg T, Marino-Enriquez A, Reis A, Corless C, et al.
Oncotarget . 2016 May; 7(27):41390-41403. PMID: 27167336
Gastrointestinal stromal tumors (GIST) exhibit a strong oncogenic dependency on KIT and KIT inhibitors confer long lasting disease stabilization in the majority of patients. Nonetheless, KIT inhibition alone does not...