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Jonathan A Hata

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Articles 12
Citations 217
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Recent Articles
1.
Lima B, Kherani A, Hata J, Cheema F, Casher J, Oz M, et al.
Heart Surg Forum . 2006 Nov; 9(5):E783-5. PMID: 17099972
Background: A risk factor summation score was previously validated to successfully predict survival after insertion of a left ventricular assist device (LVAD). We investigated whether this scoring system also predicts...
2.
Hata J, Williams M, Schroder J, Lima B, Keys J, Blaxall B, et al.
J Card Fail . 2006 Jun; 12(5):360-8. PMID: 16762799
Background: In human heart failure, increased expression of G protein-coupled receptor kinases (GRKs) causes the loss of beta-adrenergic receptor (betaAR) signaling and function. Mechanical unloading with a left ventricular assist...
3.
Felker G, Hernandez A, Rogers J, Russell S, Reinsmoen N, Rosenberg P, et al.
Clin Transpl . 2006 May; :235-41. PMID: 16704154
Since beginning cardiac transplantation in 1985, Duke University Medical Center has performed 485 de novo heart transplants in adult recipients. Our program has broadened the access of patients to transplantation...
4.
Petrofski J, Hata J, Williams M, Parsa C, Thompson R, Hanish S, et al.
J Thorac Cardiovasc Surg . 2005 Nov; 130(6):1683-90. PMID: 16308016
Objective: Approximately 50% of aortocoronary saphenous vein grafts are occluded 10 years after coronary revascularization surgery. Intimal hyperplasia, a critical component in saphenous vein graft failure, is defined by vascular...
5.
Williams M, Muhlbaier L, Schroder J, Hata J, Peterson E, Smith P, et al.
Circulation . 2005 Sep; 112(9 Suppl):I366-70. PMID: 16159847
Background: Surgeons have adopted off-pump coronary artery bypass grafting (OPCAB) in an effort to reduce the morbidity of surgical revascularization. However, long-term outcome of OPCAB compared with conventional coronary artery...
6.
Schroder J, Williams M, Hata J, Muhlbaier L, Swaminathan M, Mathew J, et al.
Circulation . 2005 Sep; 112(9 Suppl):I293-8. PMID: 16159834
Background: It is unclear if mild or moderate mitral valve regurgitation (MR) should be repaired at the time of coronary artery bypass grafting (CABG). We sought to determine the long-term...
7.
Hata J, Petrofski J, Schroder J, Williams M, Timberlake S, Pippen A, et al.
J Thorac Cardiovasc Surg . 2005 Jun; 129(6):1405-13. PMID: 15942585
Objectives: Fifty percent of human aortocoronary saphenous vein grafts are occluded after 10 years. Intimal hyperplasia is an initial step in graft occlusion and consists of vascular smooth muscle cell...
8.
Perrino C, Naga Prasad S, Schroder J, Hata J, Milano C, Rockman H
Circulation . 2005 May; 111(20):2579-87. PMID: 15897344
Background: Desensitization and downregulation of myocardial beta-adrenergic receptors (betaARs) are initiated by the increase in betaAR kinase 1 (betaARK1) levels. By interacting with betaARK1 through the phosphoinositide kinase (PIK) domain,...
9.
Hata J, Williams M, Koch W
J Mol Cell Cardiol . 2004 Jul; 37(1):11-21. PMID: 15242731
Heart failure (HF) represents one of the leading causes of morbidity and mortality in developed nations today. Although this disease process represents a final common endpoint for several entities, including...
10.
Williams M, Hata J, Schroder J, Rampersaud E, Petrofski J, Jakoi A, et al.
Circulation . 2004 Mar; 109(13):1590-3. PMID: 15051637
Background: Failing human myocardium is characterized by an attenuated contractile response to beta-adrenergic receptor (betaAR) stimulation due to changes in this signaling cascade, including increased expression and activity of the...