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Jonas Walter

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Articles 18
Citations 863
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Recent Articles
1.
Liebner T, Kilic S, Walter J, Aibara H, Narita T, Choudhary C
Nat Commun . 2024 Jun; 15(1):4962. PMID: 38862536
In all eukaryotes, acetylation of histone lysine residues correlates with transcription activation. Whether histone acetylation is a cause or consequence of transcription is debated. One model suggests that transcription promotes...
2.
Bartz M, Juttner M, Halmos F, Uhlich E, Klein M, Drumm P, et al.
Biomimetics (Basel) . 2024 Apr; 9(4). PMID: 38667248
The load-adaptive behavior of the muscles in the human musculoskeletal system offers great potential for minimizing resource and energy requirements in many technical systems, especially in drive technology and robotics....
3.
Chemla A, Arena G, Onal G, Walter J, Berenguer-Escuder C, Grossmann D, et al.
Stem Cell Res . 2023 Jun; 71:103145. PMID: 37364399
Fibroblasts from two Parkinson's disease (PD) patients carrying either the heterozygous mutation c.815G > A (Miro1 p.R272Q) or c.1348C > T (Miro1 p.R450C) in the RHOT1 gene, were converted into...
4.
Narita T, Higashijima Y, Kilic S, Liebner T, Walter J, Choudhary C
Nat Genet . 2023 Apr; 55(4):679-692. PMID: 37024579
Chromatin features are widely used for genome-scale mapping of enhancers. However, discriminating active enhancers from other cis-regulatory elements, predicting enhancer strength and identifying their target genes is challenging. Here we...
5.
Walter J, Bolognin S, Poovathingal S, Magni S, Gerard D, Antony P, et al.
Cell Rep . 2021 Oct; 37(3):109864. PMID: 34686322
Increasing evidence suggests that neurodevelopmental alterations might contribute to increase the susceptibility to develop neurodegenerative diseases. We investigate the occurrence of developmental abnormalities in dopaminergic neurons in a model of...
6.
Jarazo J, Barmpa K, Modamio J, Saraiva C, Sabate-Soler S, Rosety I, et al.
Mov Disord . 2021 Oct; 37(1):80-94. PMID: 34637165
Background: The etiology of Parkinson's disease (PD) is only partially understood despite the fact that environmental causes, risk factors, and specific gene mutations are contributors to the disease. Biallelic mutations...
7.
Narita T, Ito S, Higashijima Y, Chu W, Neumann K, Walter J, et al.
Mol Cell . 2021 Mar; 81(10):2166-2182.e6. PMID: 33765415
The metazoan-specific acetyltransferase p300/CBP is involved in activating signal-induced, enhancer-mediated transcription of cell-type-specific genes. However, the global kinetics and mechanisms of p300/CBP activity-dependent transcription activation remain poorly understood. We performed...
8.
Berenguer-Escuder C, Grossmann D, Antony P, Arena G, Wasner K, Massart F, et al.
Hum Mol Genet . 2020 Apr; 29(8):1353-1364. PMID: 32280985
Mitochondrial Rho GTPase 1 (Miro1) protein is a well-known adaptor for mitochondrial transport and also regulates mitochondrial quality control and function. Furthermore, Miro1 was associated with mitochondrial-endoplasmic reticulum (ER) contact...
9.
Nickels S, Walter J, Bolognin S, Gerard D, Jaeger C, Qing X, et al.
Parkinsonism Relat Disord . 2019 Oct; 67:48-55. PMID: 31621607
Parkinson's disease (PD) is a multifactorial disorder with complex etiology. The most prevalent PD associated mutation, LRRK2-G2019S is linked to familial and sporadic cases. Based on the multitude of genetic...
10.
Arias-Fuenzalida J, Jarazo J, Walter J, Gomez-Giro G, Forster J, Krueger R, et al.
Sci Rep . 2019 Jul; 9(1):9455. PMID: 31263238
Autophagic processes play a central role in cellular homeostasis. In pathological conditions, the flow of autophagy can be affected at multiple and distinct steps of the pathway. Current analyses tools...