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Jonas T Schnider

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Articles 14
Citations 175
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Recent Articles
1.
Feturi F, Schnider J, Fanzio P, Erbas V, Oksuz S, Sahin H, et al.
Pharm Res . 2020 Oct; 37(11):222. PMID: 33067715
Aim: The high doses of oral tacrolimus (TAC) (1,2) necessary to prevent acute rejection (AR) after vascularized composite allotransplantation (VCA) are associated with systemic adverse effects. The skin is the...
2.
Schweizer R, Schnider J, Fanzio P, Tsuji W, Kostereva N, Solari M, et al.
Plast Reconstr Surg Glob Open . 2020 Aug; 8(7):e2953. PMID: 32802651
Methods: Lewis rats were divided into 3 groups: 10 mm sciatic nerve resection ("CUT" group; n = 10), transection and repair ("REP" group; n = 10), transection and repair plus...
3.
Fisher J, Balmert S, Zhang W, Schweizer R, Schnider J, Komatsu C, et al.
Proc Natl Acad Sci U S A . 2019 Dec; 116(51):25784-25789. PMID: 31792185
For individuals who sustain devastating composite tissue loss, vascularized composite allotransplantation (VCA; e.g., hand and face transplantation) has the potential to restore appearance and function of the damaged tissues. As...
4.
Sutter D, Dzhonova D, Prost J, Bovet C, Banz Y, Rahnfeld L, et al.
Sci Rep . 2019 Jun; 9(1):9269. PMID: 31239498
Vascularized composite allotransplantation (VCA), such as hand and face transplantation, is emerging as a potential solution in patients that suffered severe injuries. However, adverse effects of chronic high-dose immunosuppression regimens...
5.
Feturi F, Weinstock M, Zhao W, Zhang W, Schnider J, Erbas V, et al.
Front Surg . 2018 Jun; 5:20. PMID: 29868602
Mycophenolic acid (MPA), is the active form of the ester prodrug mycophenolate mofetil (MMF). MMF is an FDA approved immunosuppressive drug that has been successfully used in systemic therapy in...
6.
Unadkat J, Schnider J, Feturi F, Tsuji W, Bliley J, Venkataramanan R, et al.
Plast Reconstr Surg . 2017 Jan; 139(2):403e-414e. PMID: 28121868
Background: In vascularized composite allotransplantation, medication nonadherence leads to increased acute rejections. Improving medication adherence would improve overall allograft survival. Regionally delivered immunosuppression, targeted to sites of allorecognition, may reduce...
7.
Plock J, Schnider J, Schweizer R, Zhang W, Tsuji W, Waldner M, et al.
Transplantation . 2016 Nov; 101(1):e1-e11. PMID: 27893612
Background: Cellular therapies for immunomodulation in vascularized composite allotransplantation (VCA) have gained importance due to their potential for minimization of immunosuppression. Adipose-derived (AD) mesenchymal stem cells (MSCs) especially have shown...
8.
Kostereva N, Wang Y, Fletcher D, Unadkat J, Schnider J, Komatsu C, et al.
PLoS One . 2016 Jun; 11(6):e0156149. PMID: 27272754
Impaired nerve regeneration and inadequate recovery of motor and sensory function following peripheral nerve repair remain the most significant hurdles to optimal functional and quality of life outcomes in vascularized...
9.
Plock J, Schnider J, Zhang W, Schweizer R, Tsuji W, Kostereva N, et al.
Transplantation . 2015 Jun; 99(9):1765-73. PMID: 26102613
Background: Strategies aiming at minimization or elimination of systemic immunosuppression are key immediate goals for clinical expansion of vascularized composite allotransplantation (VCA). We compared the in vitro and in vivo...
10.
Tsuji W, Schnider J, McLaughlin M, Schweizer R, Zhang W, Solari M, et al.
Front Immunol . 2015 May; 6:131. PMID: 25932028
The immunomodulatory potential of cell therapies using adipose-derived stem cells (ASCs) and bone marrow-derived mesenchymal stem cells (BM-MSCs) has been studied in vascularized composite allotransplantation (VCA). Most cell therapy-based experimental...