Jonas F Hummel
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Explore the profile of Jonas F Hummel including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
38
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Recent Articles
1.
Arnold F, Kupferschmid L, Weissenborn P, Heldmann L, Hummel J, Zareba P, et al.
Cell Mol Immunol
. 2024 Jul;
21(9):1066-1081.
PMID: 38961265
Immune-mediated nephritis is a leading cause of acute kidney injury and chronic kidney disease. While the role of B cells and antibodies has been extensively investigated in the past, the...
2.
Moeed A, Thilmany N, Beck F, Puthussery B, Ortmann N, Haimovici A, et al.
Cell Death Differ
. 2024 Jun;
31(7):924-937.
PMID: 38849575
Mitochondria react to infection with sub-lethal signals in the apoptosis pathway. Mitochondrial signals can be inflammatory but mechanisms are only partially understood. We show that activation of the caspase-activated DNase...
3.
Herr L, Fiala G, Sagar , Schaffer A, Hummel J, Zintchenko M, et al.
Sci Adv
. 2024 Mar;
10(11):eadj2802.
PMID: 38489359
Development of T cells is controlled by the signal strength of the TCR. The scaffold protein kinase D-interacting substrate of 220 kilodalton (Kidins220) binds to the TCR; however, its role...
4.
Thelen B, Schipperges V, Knorlein P, Hummel J, Arnold F, Kupferschmid L, et al.
Front Immunol
. 2023 Feb;
14:1058267.
PMID: 36756120
The T-box transcription factors T-bet and Eomesodermin regulate type 1 immune responses in innate and adaptive lymphocytes. T-bet is widely expressed in the immune system but was initially identified as...
5.
Fixemer J, Hummel J, Arnold F, Klose C, Hofherr A, Weissert K, et al.
PLoS Pathog
. 2020 Sep;
16(9):e1008870.
PMID: 32991634
The two T-box transcription factors T-bet and Eomesodermin (Eomes) are important regulators of cytotoxic lymphocytes (CTLs), such as activated CD8 T cells, which are essential in the fight against intracellular...
6.
Hummel J, Zeis P, Ebert K, Fixemer J, Konrad P, Schachtrup C, et al.
Mucosal Immunol
. 2019 Nov;
13(2):257-270.
PMID: 31712600
Natural intraepithelial lymphocytes (IELs) are thymus-derived adaptive immune cells, which are important contributors to intestinal immune homeostasis. Similar to other innate-like T cells, they are induced in the thymus through...
7.
Klose C, Hummel J, Faller L, dHargues Y, Ebert K, Tanriver Y
Mucosal Immunol
. 2017 Jul;
11(2):333-344.
PMID: 28745324
The intestine is a major immune organ with several specialized lymphoid structures and immune cells. Among these are thymus-derived natural intraepithelial lymphocytes (IELs) that lack expression of the classical co-receptors...
8.
Probst S, Daza R, Bader N, Hummel J, Weiss M, Tanriver Y, et al.
Genesis
. 2017 Jun;
55(8).
PMID: 28646547
The T-box transcription factor Eomes (also known as Tbr2) shows short-lived expression in various localized domains of the embryo, including epiblast cells during gastrulation and intermediate progenitor cells in the...