Jonas Borgel
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Explore the profile of Jonas Borgel including associated specialties, affiliations and a list of published articles.
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11
Citations
173
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Recent Articles
1.
Hou K, Borgel J, Jiang H, SantaLucia D, Kwon H, Zhuang H, et al.
Science
. 2023 Nov;
382(6670):547-553.
PMID: 37917685
In nature, nonheme iron enzymes use dioxygen to generate high-spin iron(IV)=O species for a variety of oxygenation reactions. Although synthetic chemists have long sought to mimic this reactivity, the enzyme-like...
2.
Barnett B, Evans H, Su G, Jiang H, Chakraborty R, Banyeretse D, et al.
J Am Chem Soc
. 2021 Aug;
143(36):14884-14894.
PMID: 34463495
Coordinatively unsaturated metal sites within certain zeolites and metal-organic frameworks can strongly adsorb a wide array of substrates. While many classical examples involve electron-poor metal cations that interact with adsorbates...
3.
Tanwar L, Borgel J, Lehmann J, Ritter T
Org Lett
. 2021 Jun;
23(13):5024-5027.
PMID: 34114468
Iodoarenes are versatile intermediates and common synthetic targets in organic synthesis. Here, we present a strategy for selective C-H iodination of (hetero)arenes with a broad functional group tolerance. We demonstrate...
4.
Tanwar L, Borgel J, Ritter T
J Am Chem Soc
. 2019 Nov;
141(45):17983-17988.
PMID: 31689095
Selective methylene C-H oxidation for the synthesis of alcohols with a broad scope and functional group tolerance is challenging due to the high proclivity for further oxidation of alcohols to...
5.
Ye F, Berger F, Jia H, Ford J, Wortman A, Borgel J, et al.
Angew Chem Int Ed Engl
. 2019 Aug;
58(41):14615-14619.
PMID: 31389649
Incorporation of the CF group into arenes has found increasing importance in drug discovery. Herein, we report the first photoredox-catalyzed cross-coupling of aryl thianthrenium salts with a copper-based trifluoromethyl reagent,...
6.
DAmato E, Borgel J, Ritter T
Chem Sci
. 2019 Mar;
10(8):2424-2428.
PMID: 30881670
We report a direct radical aromatic amination reaction that provides unprotected anilines with an improvement in the substrate scope compared to prior art. Hydrogen bonding by the solvent hexafluoroisopropanol to...
7.
Borgel J, Tanwar L, Berger F, Ritter T
J Am Chem Soc
. 2018 Nov;
140(47):16026-16031.
PMID: 30421917
Synthetic methods for oxidative aromatic C-O bond formation are sparse, despite their demand in metabolite synthesis for drug discovery and development. We report a novel methodology for late-stage C-O bond...
8.
Rakers L, Grill D, Matos A, Wulff S, Wang D, Borgel J, et al.
Cell Chem Biol
. 2018 May;
25(8):952-961.e12.
PMID: 29805038
Cholesterol is an essential component of most biological membranes and serves important functions in controlling membrane integrity, organization, and signaling. However, probes to follow the dynamic distribution of cholesterol in...
9.
Lee H, Borgel J, Ritter T
Angew Chem Int Ed Engl
. 2017 May;
56(24):6966-6969.
PMID: 28493645
We report a C-F reductive elimination from a characterized first-row aryl metal fluoride complex. Reductive elimination from the presented nickel(III) complexes is faster than C-F bond formation from any other...
10.
Sladojevich F, McNeill E, Borgel J, Zheng S, Ritter T
Angew Chem Int Ed Engl
. 2015 Feb;
54(12):3712-6.
PMID: 25651531
A family of practical, liquid trifluoromethylation and pentafluoroethylation reagents is described. We show how halogen bonding can be used to obtain easily handled liquid reagents from gaseous CF3I and CF3CF2I....