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Jonah N Cullen

Explore the profile of Jonah N Cullen including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 128
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Recent Articles
11.
Shelton G, Minor K, Vieira N, Kunkel L, Friedenberg S, Cullen J, et al.
Neuromuscul Disord . 2022 Aug; 32(10):836-841. PMID: 36041985
A form of dystrophinopathy with mild or subclinical neuromuscular signs has been previously reported in a family of Labrador retrievers. Markedly and persistently elevated creatine kinase activity was first noted...
12.
Shelton G, Minor K, Guo L, Thomas-Hollands A, Walsh K, Friedenberg S, et al.
Genes (Basel) . 2022 Aug; 13(8). PMID: 36011338
In this report, we describe a novel genetic basis for congenital dyserythropoietic anemia and polymyopathy in Labrador Retriever littermates characterized by incidental detection of marked microcytosis, inappropriate metarubricytosis, pelvic limb...
13.
Cullen J, Martin J, Vilella A, Treeful A, Sargan D, Bradley A, et al.
PLoS One . 2022 Jul; 17(7):e0270710. PMID: 35802654
Profiling the adaptive immune repertoire using next generation sequencing (NGS) has become common in human medicine, showing promise in characterizing clonal expansion of B cell clones through analysis of B...
14.
Shelton G, Minor K, Thomovsky S, Guo L, Friedenberg S, Cullen J, et al.
J Vet Intern Med . 2021 Dec; 36(1):279-284. PMID: 34854126
A 2-year-old female spayed dog was presented with a chronic history of short-strided gait and inability to completely open the jaw. Clinical signs were present since the dog was adopted...
15.
Shelton G, Minor K, Guo L, Friedenberg S, Cullen J, Hord J, et al.
Neuromuscul Disord . 2021 Oct; 31(11):1169-1178. PMID: 34654610
Alpha-dystroglycan (αDG) is a highly glycosylated cell surface protein with a significant role in cell-to-extracellular matrix interactions in muscle. αDG interaction with extracellular ligands relies on the activity of the...
16.
Mickelson J, Minor K, Guo L, Friedenberg S, Cullen J, Ciavarella A, et al.
Skelet Muscle . 2021 Jan; 11(1):2. PMID: 33407862
Background: A cohort of related miniature dachshund dogs with exercise intolerance, stiff gait, dysphagia, myoglobinuria, and markedly elevated serum creatine kinase activities were identified. Methods: Muscle biopsy histopathology, immunofluorescence microscopy,...
17.
Zhao J, Wang C, Totton S, Cullen J, OConnor A
PLoS One . 2019 Aug; 14(8):e0220879. PMID: 31404099
A common feature of preclinical animal experiments is repeated measurement of the outcome, e.g., body weight measured in mice pups weekly for 20 weeks. Separate time point analysis or repeated...
18.
OConnor A, Totton S, Cullen J, Ramezani M, Kalivarapu V, Yuan C, et al.
PLoS One . 2018 Jun; 13(6):e0199441. PMID: 29953471
Systematic reviews are increasingly using data from preclinical animal experiments in evidence networks. Further, there are ever-increasing efforts to automate aspects of the systematic review process. When assessing systematic bias...
19.
Makielski K, Brooks M, Wang C, Cullen J, OConnor A, LeVine D
J Vet Intern Med . 2018 Apr; 32(3):1041-1050. PMID: 29681130
Background: A method of quantifying clinical bleeding in dogs with immune thrombocytopenia (ITP) is needed because ITP patients have variable bleeding tendencies that inconsistently correlate with platelet count. A scoring...
20.
Totton S, Cullen J, Sargeant J, OConnor A
Prev Vet Med . 2018 Feb; 150:117-125. PMID: 29406078
The goal of the REFLECT Statement (Reporting guidElines For randomized controLled trials in livEstoCk and food safeTy) (published in 2010) was to provide the veterinary research community with reporting guidelines...