Jona Saemundsdottir
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Explore the profile of Jona Saemundsdottir including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir G, Steinthorsdottir V, Halldorsson G, et al.
Nat Commun
. 2023 Jun;
14(1):3453.
PMID: 37301908
Genotypes causing pregnancy loss and perinatal mortality are depleted among living individuals and are therefore difficult to find. To explore genetic causes of recessive lethality, we searched for sequence variants...
12.
Helgadottir A, Thorleifsson G, Snaebjarnarson A, Stefansdottir L, Sveinbjornsson G, Tragante V, et al.
Eur J Prev Cardiol
. 2022 Sep;
29(18):2374-2385.
PMID: 36125206
Background And Aims: The causal contribution of apolipoprotein B (apoB) particles to coronary artery disease (CAD) is established. We examined whether this atherogenic contribution is better reflected by non-high-density lipoprotein...
13.
Olafsdottir T, Bjarnadottir K, Norddahl G, Halldorsson G, Melsted P, Gunnarsdottir K, et al.
Commun Biol
. 2022 Sep;
5(1):914.
PMID: 36068292
Memory T-cell responses following SARS-CoV-2 infection have been extensively investigated but many studies have been small with a limited range of disease severity. Here we analyze SARS-CoV-2 reactive T-cell responses...
14.
Halldorsson B, Eggertsson H, Moore K, Hauswedell H, Eiriksson O, Ulfarsson M, et al.
Nature
. 2022 Jul;
607(7920):732-740.
PMID: 35859178
Detailed knowledge of how diversity in the sequence of the human genome affects phenotypic diversity depends on a comprehensive and reliable characterization of both sequences and phenotypic variation. Over the...
15.
Oskarsson G, Magnusson M, Oddsson A, Jensson B, Fridriksdottir R, Arnadottir G, et al.
Commun Biol
. 2022 Jun;
5(1):525.
PMID: 35650273
The characteristic lobulated nuclear morphology of granulocytes is partially determined by composition of nuclear envelope proteins. Abnormal nuclear morphology is primarily observed as an increased number of hypolobulated immature neutrophils,...
16.
Hjorleifsson K, Rognvaldsson S, Jonsson H, Agustsdottir A, Andresdottir M, Birgisdottir K, et al.
Clin Microbiol Infect
. 2022 Feb;
28(6):852-858.
PMID: 35182757
Objectives: The spread of SARS-CoV-2 is dependent on several factors, both biological and behavioural. The effectiveness of nonpharmaceutical interventions can be attributed largely to changes in human behaviour, but quantifying...
17.
Arnadottir G, Oddsson A, Jensson B, Gisladottir S, Simon M, Arnthorsson A, et al.
Nat Commun
. 2022 Feb;
13(1):705.
PMID: 35121750
Predicting the pathogenicity of biallelic missense variants can be challenging. Here, we use a deficit of observed homozygous carriers of missense variants, versus an expected number in a set of...
18.
Ferkingstad E, Sulem P, Atlason B, Sveinbjornsson G, Magnusson M, Styrmisdottir E, et al.
Nat Genet
. 2021 Dec;
53(12):1712-1721.
PMID: 34857953
The plasma proteome can help bridge the gap between the genome and diseases. Here we describe genome-wide association studies (GWASs) of plasma protein levels measured with 4,907 aptamers in 35,559...
19.
Fridriksdottir R, Jonsson A, Jensson B, Sverrisson K, Arnadottir G, Skarphedinsdottir S, et al.
Eur J Hum Genet
. 2021 Aug;
29(12):1819-1824.
PMID: 34462577
Malignant hyperthermia (MH) susceptibility is a rare life-threatening disorder that occurs upon exposure to a triggering agent. MH is commonly due to protein-altering variants in RYR1 and CACNA1S. The American...
20.
Eiriksdottir T, Ardal S, Jonsson B, Lund S, Ivarsdottir E, Norland K, et al.
Commun Biol
. 2021 Jun;
4(1):758.
PMID: 34145379
Predicting all-cause mortality risk is challenging and requires extensive medical data. Recently, large-scale proteomics datasets have proven useful for predicting health-related outcomes. Here, we use measurements of levels of 4,684...