Jon White
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Explore the profile of Jon White including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
2113
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Recent Articles
1.
White J, Sharma R, Balding D, Cockram J, Mackay I
Crop Sci
. 2022 Aug;
62(3):965-981.
PMID: 35915786
Association mapping using crop cultivars allows identification of genetic loci of direct relevance to breeding. Here, 150 U.K. wheat ( L.) cultivars genotyped with 23,288 single nucleotide polymorphisms (SNPs) were...
2.
Wang Z, Hopson L, Singleton S, Yang X, Jogunoori W, Mazumder R, et al.
Biochim Biophys Acta Mol Basis Dis
. 2021 Jun;
1867(10):166179.
PMID: 34082069
Emerging data show a rise in colorectal cancer (CRC) incidence in young men and women that is often chemoresistant. One potential risk factor is an alteration in the microbiome. Here,...
3.
Linner R, Biroli P, Kong E, Meddens S, Wedow R, Fontana M, et al.
Nat Genet
. 2019 Jan;
51(2):245-257.
PMID: 30643258
Humans vary substantially in their willingness to take risks. In a combined sample of over 1 million individuals, we conducted genome-wide association studies (GWAS) of general risk tolerance, adventurousness, and...
4.
Kia D, Noyce A, White J, Speed D, Nicolas A, Burgess S, et al.
Ann Neurol
. 2018 Jul;
84(2):191-199.
PMID: 30014513
Objective: Observational studies have shown that increased plasma urate is associated with lower risk of Parkinson's disease (PD), but these studies were not designed to test causality. If a causal...
5.
Mohapatra S, Batra S, Bharadwaj S, Bouvet M, Cosman B, Goel A, et al.
Dig Dis Sci
. 2018 Mar;
63(5):1123-1138.
PMID: 29572615
Colorectal cancer (CRC) accounts for ~9% of all cancers in the Veteran population, a fact which has focused a great deal of the attention of the VA's research and development...
6.
Rao S, Zaidi S, Banerjee J, Jogunoori W, Sebastian R, Mishra B, et al.
Hepatol Commun
. 2018 Feb;
1(6):477-493.
PMID: 29404474
Cancer stem cells have established mechanisms that contribute to tumor heterogeneity as well as resistance to therapy. Over 40% of hepatocellular carcinomas (HCCs) are considered to be clonal and arise...
7.
Chen J, Zaidi S, Rao S, Chen J, Phan L, Farci P, et al.
Gastroenterology
. 2017 Sep;
154(1):195-210.
PMID: 28918914
Background & Aims: Development of hepatocellular carcinoma (HCC) is associated with alterations in the transforming growth factor-beta (TGF-β) signaling pathway, which regulates liver inflammation and can have tumor suppressor or...
8.
Dale C, Fatemifar G, Palmer T, White J, Prieto-Merino D, Zabaneh D, et al.
Circulation
. 2017 May;
135(24):2373-2388.
PMID: 28500271
Background: The implications of different adiposity measures on cardiovascular disease etiology remain unclear. In this article, we quantify and contrast causal associations of central adiposity (waist-to-hip ratio adjusted for body...
9.
Fairoozy R, Cooper J, White J, Giambartolomei C, Folkersen L, Wannamethee S, et al.
Atherosclerosis
. 2017 Apr;
261:60-68.
PMID: 28456096
Background And Aims: Annexin-A2 (AnxA2) is an endogenous inhibitor of proprotein convertase subtilisin/kexin type-9 (PCSK9). The repeat-one (R1) domain of AnxA2 binds to PCSK9, blocking its ability to promote degradation...
10.
Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong L, et al.
Hepatology
. 2017 Jan;
65(2):678-693.
PMID: 28114741
Conclusion: Dysfunctional transforming growth factor β/β2SP signaling impacts the processing of genotoxic metabolites by altering the Fanconi anemia DNA repair pathway. (Hepatology 2017;65:678-693).