Jon R Sobus
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Explore the profile of Jon R Sobus including associated specialties, affiliations and a list of published articles.
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73
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1401
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Recent Articles
11.
Boyce M, Favela K, Bonzo J, Chao A, Lizarraga L, Moody L, et al.
Front Toxicol
. 2023 Feb;
5:1051483.
PMID: 36742129
Understanding the metabolic fate of a xenobiotic substance can help inform its potential health risks and allow for the identification of signature metabolites associated with exposure. The need to characterize...
12.
Isaacs K, Egeghy P, Dionisio K, Phillips K, Zidek A, Ring C, et al.
J Expo Sci Environ Epidemiol
. 2022 Nov;
32(6):820-832.
PMID: 36435938
The rapid characterization of risk to humans and ecosystems from exogenous chemicals requires information on both hazard and exposure. The U.S. Environmental Protection Agency's ToxCast program and the interagency Tox21...
13.
Chao A, Grossman J, Carberry C, Lai Y, Williams A, Minucci J, et al.
Environ Int
. 2022 Aug;
167:107385.
PMID: 35952468
Background: Environmental health research has recently undergone a dramatic shift, with ongoing technological advancements allowing for broader coverage of exposure and molecular biology signatures. Approaches to integrate such measures are...
14.
Fisher C, Peter K, Newton S, Schaub A, Sobus J
Anal Bioanal Chem
. 2022 Jul;
414(22):6455-6471.
PMID: 35796784
Non-targeted analysis (NTA) using high-resolution mass spectrometry has enabled the detection and identification of unknown and unexpected compounds of interest in a wide range of sample matrices. Despite these benefits...
15.
Isaacs K, Wall J, Williams A, Hobbie K, Sobus J, Ulrich E, et al.
Sci Data
. 2022 Jun;
9(1):314.
PMID: 35710792
Direct monitoring of chemical concentrations in different environmental and biological media is critical to understanding the mechanisms by which human and ecological receptors are exposed to exogenous chemicals. Monitoring data...
16.
Groff 2nd L, Grossman J, Kruve A, Minucci J, Lowe C, McCord J, et al.
Anal Bioanal Chem
. 2022 Jun;
414(17):4919-4933.
PMID: 35699740
Non-targeted analysis (NTA) methods are widely used for chemical discovery but seldom employed for quantitation due to a lack of robust methods to estimate chemical concentrations with confidence limits. Herein,...
17.
McCord J, Groff 2nd L, Sobus J
Environ Int
. 2022 Apr;
158:107011.
PMID: 35386928
Chemical risk assessments follow a long-standing paradigm that integrates hazard, dose-response, and exposure information to facilitate quantitative risk characterization. Targeted analytical measurement data directly support risk assessment activities, as well...
18.
Place B, Ulrich E, Challis J, Chao A, Du B, Favela K, et al.
Anal Chem
. 2021 Nov;
93(49):16289-16296.
PMID: 34842413
Non-targeted analysis (NTA) encompasses a rapidly evolving set of mass spectrometry techniques aimed at characterizing the chemical composition of complex samples, identifying unknown compounds, and/or classifying samples, without prior knowledge...
19.
Lowe C, Isaacs K, Mceachran A, Grulke C, Sobus J, Ulrich E, et al.
Anal Bioanal Chem
. 2021 Oct;
413(30):7495-7508.
PMID: 34648052
With the increasing availability of high-resolution mass spectrometers, suspect screening and non-targeted analysis are becoming popular compound identification tools for environmental researchers. Samples of interest often contain a large (unknown)...
20.
Peter K, Phillips A, Knolhoff A, Gardinali P, Manzano C, Miller K, et al.
Anal Chem
. 2021 Oct;
93(41):13870-13879.
PMID: 34618419
Non-targeted analysis (NTA) workflows using mass spectrometry are gaining popularity in many disciplines, but universally accepted reporting standards are nonexistent. Current guidance addresses limited elements of NTA reporting-most notably, identification...