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John Trinder

Explore the profile of John Trinder including associated specialties, affiliations and a list of published articles. Areas
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Articles 131
Citations 3085
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Recent Articles
1.
Woolfall K, Paddock K, Watkins M, Kearney A, Neville K, Frith L, et al.
J Intensive Care Soc . 2024 Sep; 25(1):95-101. PMID: 39323597
Clinical research in intensive care units (ICUs) is essential for improving treatments for critically ill patients. However, invitations to participate in clinical research in this situation pose numerous challenges. Studies...
2.
Jordan A, Woods M, Cori J, Chan J, Nicholas C, Semmler J, et al.
J Appl Physiol (1985) . 2024 Sep; 137(5):1409-1417. PMID: 39323393
High activity of upper airway dilator muscles is thought to be critical in preventing sleep-related upper airway collapse. To date, most of the research regarding upper airway dilator muscles has...
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Dawson A, Avraam J, Nicholas C, Kay A, Thornton T, Feast N, et al.
Sleep . 2023 Jul; 47(1). PMID: 37503934
Study Objectives: Transient arousal from sleep has been shown to elicit a prolonged increase in genioglossus muscle activity that persists following the return to sleep and which may protect against...
5.
Avraam J, Dawson A, Nicholas C, Fridgant M, Fan F, Kay A, et al.
Exp Physiol . 2022 Dec; 108(3):491-502. PMID: 36533973
New Findings: What is the central question of this study? How does alcohol intake, which worsens obstructive sleep apnoea, alter motor control of the genioglossus muscle, an upper airway dilator,...
6.
Paddock K, Woolfall K, Kearney A, Pattison N, Frith L, Gamble C, et al.
BMJ Open . 2022 Nov; 12(11):e066149. PMID: 36375987
Objectives: Obtaining informed consent from patients in intensive care units (ICUs) prior to enrolment in a study is practically and ethically complex. Decisions about the participation of critically ill patients...
7.
Wen C, Nicholas C, Howard M, Trinder J, Jordan A
Aerosp Med Hum Perform . 2022 Jan; 93(1):50-53. PMID: 35063056
Airline cabin crew experience high levels of fatigue and sleepiness. Whether these are solely related to their work schedules/jetlag or are in part related to individual factors is unknown. The...
8.
Silversides J, McMullan R, Emerson L, Bradbury I, Bannard-Smith J, Szakmany T, et al.
Intensive Care Med . 2021 Dec; 48(2):190-200. PMID: 34913089
Purpose: Fluid overload is common in critical illness and is associated with mortality. This study investigated the feasibility of a randomised trial comparing conservative fluid administration and deresuscitation (active removal...
9.
Toner P, Boyle A, McNamee J, Callaghan K, Nutt C, Johnston P, et al.
Chest . 2021 Nov; 161(5):1275-1284. PMID: 34785236
Background: There is no pharmacologic treatment for ARDS. Platelets play an important role in the pathophysiology of ARDS. Preclinical, observational, and clinically relevant models of ARDS indicate aspirin as a...
10.
Avraam J, Dawson A, Feast N, Fan F, Fridgant M, Kay A, et al.
Sleep . 2021 Apr; 44(9). PMID: 33822200
Study Objectives: Genioglossus (GG) after-discharge is thought to protect against pharyngeal collapse by minimizing periods of low upper airway muscle activity. How GG after-discharge occurs and which single motor units...