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John T Granton

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Articles 96
Citations 2698
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Recent Articles
1.
Jogendran R, Upagupta C, Pankiw M, Sless R, Karvasarski E, Granton J, et al.
Can J Cardiol . 2025 Feb; PMID: 39922307
Background: Broadly speaking, right heart failure can be defined as a clinical syndrome with signs and symptoms of heart failure resulting from right ventricular dysfunction, as evidenced by abnormal structure...
2.
Warren B, Tan K, Jaberi A, Donahoe L, de Perrot M, McInnis M, et al.
J Endovasc Ther . 2024 Dec; :15266028241307848. PMID: 39711514
Background: Pulmonary embolism (PE) is an important cause of death and disability. Advances in catheter-directed therapies have led to the use of devices, such as the Inari FlowTriever and Penumbra...
3.
Wright S, Brunner N, Granton J, Mak S
Can J Cardiol . 2024 Dec; PMID: 39681160
No abstract available.
4.
Savale L, Benazzo A, Corris P, Keshavjee S, Levine D, Mercier O, et al.
Eur Respir J . 2024 Aug; 64(4). PMID: 39209471
Despite the progress made in medical therapies for treating pulmonary hypertension (PH), a subset of patients remain susceptible to developing a maladaptive right ventricular phenotype. The effective management of end-stage...
5.
Nikouline A, Del Sorbo L, Granton J
Trends Anaesth Crit Care . 2024 Apr; 39:10-11. PMID: 38620830
Acute Respiratory Distress Syndrome (ARDS) accounts for 10% of all intensive care unit admissions and mortality remains exceedingly high ranging from 35 to 46%. Prone positioning has demonstrated benefit as...
6.
Wright S, Goodman J, Sasson Z, Granton J, Mak S
J Appl Physiol (1985) . 2024 Feb; 136(4):901-907. PMID: 38420677
The left atrium (LA) mediates cardiopulmonary interactions. During ventricular systole, the LA functions as a compliant reservoir that is coupled to the left ventricle (LV) and offloads volume from the...
7.
Osman S, Girdharry N, Karvasarski E, Bentley R, Wright S, Sharif N, et al.
Pulm Circ . 2024 Jan; 14(1):e12331. PMID: 38249723
Chronic thromboembolic pulmonary disease (CTEPD) is characterized by organized nonresolving thrombi in pulmonary arteries (PA). In CTEPD with pulmonary hypertension (PH), chronic thromboembolic PH (CTEPH), early wave reflection results in...
8.
Man H, Moosa V, Singh A, Wu L, Granton J, Juvet S, et al.
Front Genet . 2023 Dec; 14:1281538. PMID: 38075698
Awareness of RNA-based therapies has increased after the widespread adoption of mRNA vaccines against SARS-CoV-2 during the COVID-19 pandemic. These mRNA vaccines had a significant impact on reducing lung disease...
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Karvasarski E, Bentley R, Buchan T, Valle F, Wright S, Chang I, et al.
Physiol Rep . 2023 Jan; 11(1):e15559. PMID: 36636024
Exercise imposes increased pulmonary vascular afterload based on rises in pulmonary artery (PA) wedge pressure, declines in PA compliance, and resistance-compliance time. In health, afterload stress stabilizes during steady-state exercise....