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John R Strahler

Explore the profile of John R Strahler including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 730
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Recent Articles
1.
Talkish J, Biedka S, Jakovljevic J, Zhang J, Tang L, Strahler J, et al.
RNA . 2016 Apr; 22(6):852-66. PMID: 27036125
In higher eukaryotes, pre-rRNA processing occurs almost exclusively post-transcriptionally. This is not the case in rapidly dividing yeast, as the majority of nascent pre-rRNAs are processed cotranscriptionally, with cleavage at...
2.
Ramacciotti E, Hawley A, Wrobleski S, Myers Jr D, Strahler J, Andrews P, et al.
Thromb Res . 2010 Feb; 125(6):e269-74. PMID: 20156641
Background: Microparticles (MP) are submicron size membrane vesicles released from activated cells that are associated with thrombosis and inflammation. MP present diverse biological expressions that may be linked to a...
3.
Chen X, Sans M, Strahler J, Karnovsky A, Ernst S, Michailidis G, et al.
J Proteome Res . 2009 Dec; 9(2):885-96. PMID: 19954227
The rough endoplasmic reticulum (RER) is a central organelle for synthesizing and processing digestive enzymes and alteration of ER functions may participate in the pathogenesis of acute pancreatitis (AP). To...
4.
Vellaichamy A, Sreekumar A, Strahler J, Rajendiran T, Yu J, Varambally S, et al.
PLoS One . 2009 Sep; 4(9):e7075. PMID: 19763266
Prostate cancer remains the most common malignancy among men in United States, and there is no remedy currently available for the advanced stage hormone-refractory cancer. This is partly due to...
5.
Keshamouni V, Jagtap P, Michailidis G, Strahler J, Kuick R, Reka A, et al.
J Proteome Res . 2009 Jan; 8(1):35-47. PMID: 19118450
To gain insights into how TGF-beta regulates epithelial-mesenchymal transition (EMT), we assessed the time course of proteins and mRNAs during EMT by multiplex iTRAQ labeling and 2D-LC-MS/MS, and by hybridization,...
6.
Abdullah N, Kachman M, Walker A, Hawley A, Wrobleski S, Myers D, et al.
Clin Appl Thromb Hemost . 2008 Nov; 15(2):201-8. PMID: 19028772
Microparticles are small membrane vesicles released from activated cells and are associated with thrombosis and inflammation. Microparticle contain a unique subset of surface protein derived form the parent cell and...
7.
Christensen J, Byrd S, Walker A, Strahler J, Andrews P, Imperiale M
J Virol . 2008 Jul; 82(18):9086-93. PMID: 18614642
Assembly of adenovirus particles is thought to be similar to that of bacteriophages, in which the double-stranded DNA genome is inserted into a preformed empty capsid. Previous studies from our...
8.
Yocum A, Gratsch T, Leff N, Strahler J, Hunter C, Walker A, et al.
Mol Cell Proteomics . 2008 Feb; 7(4):750-67. PMID: 18304949
Elucidating the complex combinations of growth factors and signaling molecules that maintain pluripotency or, alternatively, promote the controlled differentiation of human embryonic stem cells (hESCs) has important implications for the...
9.
Leichert L, Gehrke F, Gudiseva H, Blackwell T, Ilbert M, Walker A, et al.
Proc Natl Acad Sci U S A . 2008 Feb; 105(24):8197-202. PMID: 18287020
Antimicrobial levels of reactive oxygen species (ROS) are produced by the mammalian host defense to kill invading bacteria and limit bacterial colonization. One main in vivo target of ROS is...
10.
Falkner J, Kachman M, Veine D, Walker A, Strahler J, Andrews P
J Am Soc Mass Spectrom . 2007 Mar; 18(5):850-5. PMID: 17329120
A current focus of proteomics research is the establishment of acceptable confidence measures in the assignment of protein identifications in an unknown sample. Development of new algorithmic approaches would greatly...