John R Charpie
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Explore the profile of John R Charpie including associated specialties, affiliations and a list of published articles.
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44
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1000
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Recent Articles
1.
Sznycer-Taub N, Lowery R, Yu S, Owens G, Charpie J
Pediatr Cardiol
. 2023 Sep;
45(1):143-149.
PMID: 37698698
Recent studies have suggested worse outcomes in patients exposed to hyperoxia while supported on veno-arterial extracorporeal membrane oxygenation (VA-ECMO). However, there are no data regarding the effect of reducing hyperoxia...
2.
Gaies M, Olive M, Owens G, Charpie J, Zhang W, Pasquali S, et al.
Circ Cardiovasc Qual Outcomes
. 2023 Feb;
16(2):e009277.
PMID: 36727516
Background: Hospitals are increasingly likely to implement clinical informatics tools to improve quality of care, necessitating rigorous approaches to evaluate effectiveness. We leveraged a multi-institutional data repository and applied causal...
3.
Peng Y, Major T, Deatrick K, Mohammed A, Jeakle M, Charpie J
Int J Cardiol
. 2022 Aug;
368:62-68.
PMID: 35987313
Background: Nicorandil, an adenosine triphosphate-sensitive potassium channel agonist and nitric oxide donor, is a coronary vasodilator used to treat ischemia-induced chest pain, but it's potential cardioprotective benefits during open heart...
4.
Rooney S, Reynolds E, Banerjee M, Pasquali S, Charpie J, Gaies M, et al.
Cardiol Young
. 2021 Dec;
32(10):1649-1656.
PMID: 34924086
Background: Cardiac intensivists frequently assess patient readiness to wean off mechanical ventilation with an extubation readiness trial despite it being no more effective than clinician judgement alone. We evaluated the...
5.
Manning L, Schumacher K, Friedland-Little J, Yu S, Lowery R, Goldstein B, et al.
Am J Cardiol
. 2021 Jul;
155:128-134.
PMID: 34315570
Fontan palliation has improved survival for single ventricle patients, but long-term complications persist including cardiovascular dysfunction, neurohormonal abnormalities, and protein-losing enteropathy (PLE). Although chronic inflammation contributes to morbidity, an association...
6.
Peng Y, Major T, Mohammed A, Deatrick K, Charpie J
J Cardiothorac Surg
. 2020 Jun;
15(1):134.
PMID: 32522213
Background: In a rabbit model of cardiopulmonary bypass (CPB) and cardioplegic arrest, we previously showed that hyperoxic myocardial reperfusion was associated with increased left ventricular (LV) systolic dysfunction and myocardial...
7.
Gaies M, Pasquali S, Banerjee M, Dimick J, Birkmeyer J, Zhang W, et al.
J Am Coll Cardiol
. 2019 Nov;
74(22):2786-2795.
PMID: 31779793
Background: Patients undergoing complex pediatric cardiac surgery remain at considerable risk of mortality and morbidity, and variation in outcomes exists across hospitals. The Pediatric Cardiac Critical Care Consortium (PC4) was...
8.
Gaies M, Anderson J, Kipps A, Lorts A, Madsen N, Marino B, et al.
Cardiol Young
. 2018 Dec;
29(2):111-118.
PMID: 30567622
Optimising short- and long-term outcomes for children and patients with CHD depends on continued scientific discovery and translation to clinical improvements in a coordinated effort by multiple stakeholders. Several challenges...
9.
Peng Y, Mohammed A, Deatrick K, Major T, Cheng D, Charpie I, et al.
Semin Thorac Cardiovasc Surg
. 2018 Oct;
31(2):188-198.
PMID: 30278268
The objectives were to investigate if after hypoxia or ischemia, normoxic reperfusion is associated with less oxidant stress (OS), inflammation, and myocardial injury than hyperoxic reperfusion. In this study, cardiomyocytes...
10.
Pasquali S, Ravishankar C, Romano J, Kane K, Viers S, Kennedy A, et al.
Cardiol Young
. 2017 Feb;
26(8):1590-1596.
PMID: 28148316
Background: With improvements in early survival following congenital heart surgery, it has become increasingly important to understand longer-term outcomes; however, routine collection of these data is challenging and remains very...