John P Kirkpatrick
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Explore the profile of John P Kirkpatrick including associated specialties, affiliations and a list of published articles.
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141
Citations
3242
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Recent Articles
1.
Zhao J, Vaios E, Yang Z, Lu K, Floyd S, Yang D, et al.
Med Phys
. 2025 Jan;
PMID: 39878595
Background: Stereotactic radiosurgery (SRS) is widely used for managing brain metastases (BMs), but an adverse effect, radionecrosis, complicates post-SRS management. Differentiating radionecrosis from tumor recurrence non-invasively remains a major clinical...
2.
Codutti L, Kirkpatrick J, Zur Lage S, Carlomagno T
Biophys J
. 2024 Oct;
123(22):3884-3897.
PMID: 39367603
DEAD-box helicases use ATP to unwind short double-stranded RNA (dsRNA). The helicase core consists of two discrete domains, termed RecA_N and RecA_C. The nucleotide binding site is harbored in RecA_N,...
3.
Weller M, Remon J, Rieken S, Vollmuth P, Ahn M, Minniti G, et al.
Cancer Treat Rev
. 2024 Aug;
130:102807.
PMID: 39151281
Up to 40% of patients with non-small cell lung cancer (NSCLC) develop central nervous system (CNS) metastases. Current treatments for this subgroup of patients with advanced NSCLC include local therapies...
4.
Leng J, Su C, Carpenter D, Floyd W, Vaios E, Shenker R, et al.
J Radiosurg SBRT
. 2024 Aug;
9(2):91-99.
PMID: 39087065
Purpose: To investigate whether TP53 variants may be correlated with overall survival and local control following stereotactic radiosurgery (SRS) for brain metastases (BMs) from non-small cell lung cancer (NSCLC). Methods:...
5.
Karanth M, Kirkpatrick J, Krausze J, Schmelz S, Scrima A, Carlomagno T
Sci Adv
. 2024 Jun;
10(25):eadm9404.
PMID: 38896613
In the quest for new bioactive substances, nonribosomal peptide synthetases (NRPS) provide biodiversity by synthesizing nonproteinaceous peptides with high cellular activity. NRPS machinery consists of multiple modules, each catalyzing a...
6.
Leng J, Carpenter D, Huang C, Qazi J, Arshad M, Mullikin T, et al.
Adv Radiat Oncol
. 2024 May;
9(6):101475.
PMID: 38690297
Purpose: Clinical and imaging surveillance of patients with brain metastases is important after stereotactic radiosurgery (SRS) because many will experience intracranial progression (ITCP) requiring multidisciplinary management. The prognostic significance of...
7.
Fairchild A, Salama J, Godfrey D, Wiggins W, Ackerson B, Oyekunle T, et al.
J Neurooncol
. 2024 Feb;
167(1):219-227.
PMID: 38340295
Purpose: During stereotactic radiosurgery (SRS) planning for brain metastases (BM), brain MRIs are reviewed to select appropriate targets based on radiographic characteristics. Some BM are difficult to detect and/or definitively...
8.
Floyd W, Carpenter D, Vaios E, Shenker R, Hendrickson P, Adamson J, et al.
Adv Radiat Oncol
. 2024 Jan;
9(1):101320.
PMID: 38260227
Purpose: Genetic variants affecting the radiation response protein ataxia-telangiectasia mutated (ATM) have been associated with increased adverse effects of radiation but also with improved local control after conventional radiation therapy....
9.
Vaios E, Shenker R, Hendrickson P, Wan Z, Niedzwiecki D, Winter S, et al.
Int J Radiat Oncol Biol Phys
. 2023 Dec;
118(5):1507-1518.
PMID: 38097090
Purpose: The intracranial benefit of offering dual immune-checkpoint inhibition (D-ICPI) with ipilimumab and nivolumab to patients with melanoma or non-small cell lung cancer (NSCLC) receiving stereotactic radiosurgery (SRS) for brain...
10.
Foreman B, Mullikin T, Floyd S, Kelsey C, Patel M, Peters K, et al.
Neurooncol Adv
. 2023 Sep;
5(1):vdad097.
PMID: 37706200
Background: Primary central nervous system lymphoma (PCNSL) is an aggressive diffuse large B-cell lymphoma. Treatment approaches are historically associated with neurotoxicity, particularly with high-dose whole-brain radiotherapy (WBRT). We hypothesized that...