John P Barton
Overview
Explore the profile of John P Barton including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
755
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Recent Articles
1.
Gao Y, Barton J
Proc Natl Acad Sci U S A
. 2025 Feb;
122(8):e2405379122.
PMID: 39970000
Natural selection often acts on multiple traits simultaneously. For example, the virus HIV-1 faces pressure to evade host immunity while also preserving replicative fitness. While past work has studied selection...
2.
Ashton E, Brenton M, Wilson J, Barton J, Wilson R, Strickland D, et al.
ACS Appl Energy Mater
. 2025 Jan;
8(2):1112-1125.
PMID: 39886449
A low-cost method of green hydrogen production via the modification of a lead acid battery has been achieved, resulting in a hydrogen flow rate of 5.3 L min from a...
3.
Lee B, Quadeer A, Sohail M, Finney E, Ahmed S, McKay M, et al.
Nat Commun
. 2025 Jan;
16(1):441.
PMID: 39774959
New and more transmissible variants of SARS-CoV-2 have arisen multiple times over the course of the pandemic. Rapidly identifying mutations that affect transmission could improve our understanding of viral biology...
4.
Shimagaki K, Barton J
bioRxiv
. 2024 Oct;
PMID: 39464126
Epistasis can profoundly influence evolutionary dynamics. Temporal genetic data, consisting of sequences sampled repeatedly from a population over time, provides a unique resource to understand how epistasis shapes evolution. However,...
5.
Rodriguez-Horta E, Strahan J, Dinner A, Barton J
bioRxiv
. 2024 Oct;
PMID: 39416020
Multiple SARS-CoV-2 variants have arisen during the first years of the pandemic, often bearing many new mutations. Several explanations have been offered for the surprisingly sudden emergence of multiple mutations...
6.
Hong Z, Shimagaki K, Barton J
Bioinformatics
. 2024 Aug;
40(8).
PMID: 39115383
Summary: Deep mutational scanning (DMS) experiments provide a powerful method to measure the functional effects of genetic mutations at massive scales. However, the data generated from these experiments can be...
7.
Shimagaki K, Lynch R, Barton J
bioRxiv
. 2024 Jul;
PMID: 39071321
Human immunodeficiency virus (HIV)-1 exhibits remarkable genetic diversity. For this reason, an effective HIV-1 vaccine must elicit antibodies that can neutralize many variants of the virus. While broadly neutralizing antibodies...
8.
Li Y, Barton J
Mol Biol Evol
. 2024 Mar;
41(4).
PMID: 38507665
In evolving populations where the rate of beneficial mutations is large, subpopulations of individuals with competing beneficial mutations can be maintained over long times. Evolution with this kind of clonal...
9.
10.
Hong Z, Barton J
bioRxiv
. 2024 Feb;
PMID: 38352383
Deep mutational scanning (DMS) experiments provide a powerful method to measure the functional effects of genetic mutations at massive scales. However, the data generated from these experiments can be difficult...