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John Monaghan

Explore the profile of John Monaghan including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 1097
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Recent Articles
1.
Horne K, Viramontes-Horner D, Packington R, Monaghan J, Shaw S, Akani A, et al.
Kidney Int . 2023 Aug; 104(6):1185-1193. PMID: 37611867
Acute kidney injury (AKI) is associated with adverse long-term outcomes, but many studies are retrospective, focused on specific patient groups or lack adequate comparators. The ARID (AKI Risk in Derby)...
2.
Guo L, Kim H, Wang H, Monaghan J, Freyermuth F, Sung J, et al.
Cell . 2018 Apr; 173(3):677-692.e20. PMID: 29677512
RNA-binding proteins (RBPs) with prion-like domains (PrLDs) phase transition to functional liquids, which can mature into aberrant hydrogels composed of pathological fibrils that underpin fatal neurodegenerative disorders. Several nuclear RBPs...
3.
Rudich P, Snoznik C, Watkins S, Monaghan J, Pandey U, Lamitina S
Hum Mol Genet . 2017 Oct; 26(24):4916-4928. PMID: 29036691
A hexanucleotide repeat expansion mutation in the C9orf72 gene represents a prevalent genetic cause of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Non-canonical translation of this...
4.
Horne K, Packington R, Monaghan J, Reilly T, Selby N
BMJ Open . 2017 Apr; 7(3):e015316. PMID: 28360257
Objectives: Using a prospective study design, we aimed to characterise the effect of acute kidney injury (AKI) on long-term changes in renal function in a general hospital population. Participants: Hospitalised...
5.
Daigle J, Krishnamurthy K, Ramesh N, Casci I, Monaghan J, McAvoy K, et al.
Acta Neuropathol . 2016 Jan; 131(4):605-20. PMID: 26728149
Amyotrophic lateral sclerosis is characterized by progressive loss of motor neurons in the brain and spinal cord. Mutations in several genes, including FUS, TDP43, Matrin 3, hnRNPA2 and other RNA-binding...
6.
Scaramuzzino C, Casci I, Parodi S, Lievens P, Polanco M, Milioto C, et al.
Neuron . 2015 Jan; 85(1):88-100. PMID: 25569348
Polyglutamine expansion in androgen receptor (AR) is responsible for spinobulbar muscular atrophy (SBMA) that leads to selective loss of lower motor neurons. Using SBMA as a model, we explored the...
7.
Wen X, Tan W, Westergard T, Krishnamurthy K, Markandaiah S, Shi Y, et al.
Neuron . 2014 Dec; 84(6):1213-25. PMID: 25521377
Expanded GGGGCC (G4C2) nucleotide repeats within the C9ORF72 gene are the most common genetic mutation associated with both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Sense and antisense transcripts...
8.
Horne K, Packington R, Monaghan J, Reilly T, McIntyre C, Selby N
Nephron Clin Pract . 2014 Dec; 128(1-2):192-200. PMID: 25472765
Background: Acute kidney injury (AKI) is common in hospitalised patients and is associated with adverse long-term consequences. There is an urgent need to understand these sequelae in general hospitalised patients...
9.
Lord G, Monaghan J
Biomed Chromatogr . 2014 May; 28(6):725. PMID: 24861735
No abstract available.
10.
Scaramuzzino C, Monaghan J, Milioto C, Lanson Jr N, Maltare A, Aggarwal T, et al.
PLoS One . 2013 Apr; 8(4):e61576. PMID: 23620769
Amyotrophic lateral sclerosis (ALS) is a late onset and progressive motor neuron disease. Mutations in the gene coding for fused in sarcoma/translocated in liposarcoma (FUS) are responsible for some cases...