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John M Pellock

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Articles 64
Citations 1179
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Recent Articles
1.
Lewis D, Voyvodic J, Shinnar S, Chan S, Bello J, Moshe S, et al.
Epilepsia . 2024 Apr; 65(6):1568-1580. PMID: 38606600
Objective: This study was undertaken to determine whether hippocampal T2 hyperintensity predicts sequelae of febrile status epilepticus, including hippocampal atrophy, sclerosis, and mesial temporal lobe epilepsy. Methods: Acute magnetic resonance...
2.
Pellock J, Arzimanoglou A, DCruz O, Holmes G, Nordli D, Shinnar S
Epilepsia . 2017 Jul; 58(10):1686-1696. PMID: 28755452
Expediting pediatric access to new antiseizure drugs is particularly compelling, because epileptic seizures are the most common serious neurological symptom in children. Analysis of antiepileptic drug (AED) efficacy outcomes of...
3.
Wadsworth I, Jaki T, Sills G, Appleton R, Cross J, Marson A, et al.
CNS Drugs . 2016 Sep; 30(11):1011-1017. PMID: 27623676
Data from clinical trials in adults, extrapolated to predict benefits in paediatric patients, could result in fewer or smaller trials being required to obtain a new drug licence for paediatrics....
4.
Hesdorffer D, Shinnar S, Lax D, Pellock J, Nordli Jr D, Seinfeld S, et al.
Epilepsia . 2016 Jun; 57(7):1042-7. PMID: 27265870
Objectives: To identify risk and risk factors for developing a subsequent febrile seizure (FS) in children with a first febrile status epilepticus (FSE) compared to a first simple febrile seizure...
5.
Pellock J, Faught E, Foroozan R, Sergott R, Shields W, Ziemann A, et al.
Epilepsy Behav . 2016 May; 60:174-180. PMID: 27208827
Vigabatrin (Sabril®) is an antiepileptic drug (AED) currently indicated in the US as a monotherapy for patients 1month to 2years of age with infantile spasms (IS) and as adjunctive therapy...
6.
Clark A, Pellock J, Holmay M, Anders B, Cloyd J
Epilepsy Behav . 2016 Mar; 57(Pt A):105-110. PMID: 26943947
Objective: The objectives of these two studies were to determine if beads from extended-release topiramate capsules sprinkled onto soft food are bioequivalent to the intact capsule and if beads from...
7.
Krauss G, Faught E, Foroozan R, Pellock J, Sergott R, Shields W, et al.
Epilepsy Behav . 2016 Jan; 56:15-9. PMID: 26807550
Vigabatrin (Sabril®), approved in the US in 2009, is currently indicated as adjunctive therapy for refractory complex partial seizures (rCPS) in patients ≥ 10 years old who have responded inadequately...
8.
Pellock J, Brittain S
Epilepsy Behav . 2016 Jan; 55:21-3. PMID: 26724400
"Forgiveness" - the difference between a drug's postdose duration of action and its prescribed dosing interval - estimates the margin of therapeutic effect following a missed dose. Because this margin...
9.
Seinfeld S, Pellock J, Kjeldsen M, Otto Nakken K, Corey L
Pediatr Neurol . 2015 Dec; 55:14-6. PMID: 26638777
Background: A history of complex febrile seizures can increase the risk of epilepsy, but the role of genetic factors is unclear. This analysis evaluated the relationship between febrile seizures and...
10.
Hawley S, Ablah E, Hesdorffer D, Pellock J, Lindeman D, Paschal A, et al.
Epilepsy Behav . 2015 Nov; 53:190-6. PMID: 26588587
Epilepsy is one of the most common disabling neurological disorders, but significant gaps exist in our knowledge about childhood epilepsy in rural populations. The present study assessed the prevalence of...