» Authors » John M Nicholls

John M Nicholls

Explore the profile of John M Nicholls including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 109
Citations 6200
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Jiao Y, Tong C, Zhao L, Zhang Y, Nicholls J, Rainer T
Lab Anim Res . 2024 May; 40(1):18. PMID: 38741131
Community-acquired respiratory infection is the commonest cause of sepsis presenting to emergency departments. Yet current experimental animal models simulate peritoneal sepsis with intraperitoneal (I.P.) injection of lipopolysaccharide (LPS) as the...
2.
Chan R, Chan M, Agnihothram S, Chan L, Kuok D, Fong J, et al.
J Virol . 2024 Mar; 98(4):e0037924. PMID: 38497665
No abstract available.
3.
So R, Chu D, Hui K, Mok C, Shum M, Sanyal S, et al.
J Virol . 2023 Dec; 97(12):e0136923. PMID: 38038429
Viral host adaptation plays an important role in inter-species transmission of coronaviruses and influenza viruses. Multiple human-adaptive mutations have been identified in influenza viruses but not so far in MERS-CoV...
4.
Hui K, Chin A, Ehret J, Ng K, Peiris M, Poon L, et al.
Int J Environ Res Public Health . 2023 Aug; 20(16). PMID: 37623181
Background: The COVID-19 pandemic from 2019 to 2022 devastated many aspects of life and the economy, with the commercial aviation industry being no exception. One of the major concerns during...
5.
Lan Y, van Leur S, Fernando J, Wong H, Kampmann M, Siu L, et al.
Nat Commun . 2023 May; 14(1):2698. PMID: 37164963
Infection by many (+)RNA viruses is accompanied by ER-expansion and membrane remodelling to form viral replication organelles, followed by assembly and secretion of viral progenies. We previously identified that virus-triggered...
6.
Hui K, Ho J, Ng K, Cheng S, Sit K, Au T, et al.
Emerg Infect Dis . 2023 Apr; 29(6):1210-1214. PMID: 37095078
Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed...
7.
So R, Chu D, Hui K, Mok C, Sanyal S, Nicholls J, et al.
bioRxiv . 2023 Apr; PMID: 37034576
Middle East respiratory syndrome coronavirus (MERS-CoV) causes zoonotic disease. Dromedary camels are the source of zoonotic infection. We identified a mutation of amino acid leucine to phenylalanine in the codon...
8.
Chu J, Gu H, Sun W, Fan R, Nicholls J, Valkenburg S, et al.
Virus Res . 2022 Oct; 323:198991. PMID: 36302472
Rapid antigenic evolution of the influenza A virus surface antigen hemagglutinin undermines protection conferred by seasonal vaccines. Protective correlates targeted by universal vaccines such as cytotoxic T cells or HA...
9.
Hui K, Ng K, Ho J, Yeung H, Ching R, Gu H, et al.
EBioMedicine . 2022 Aug; 83:104232. PMID: 35988466
Background: The Omicron BA.2 sublineage has replaced BA.1 worldwide and has comparable levels of immune evasion to BA.1. These observations suggest that the increased transmissibility of BA.2 cannot be explained...
10.
Su W, Choy K, Gu H, Sia S, Cheng K, Nizami S, et al.
J Infect Dis . 2022 Jul; 227(10):1143-1152. PMID: 35776136
Background: The epidemiological advantage of Omicron variant is evidenced by its rapid spread and the ability to outcompete prior variants. Among Omicron sublineages, early outbreaks were dominated by BA.1, while...