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John M McCurley

Explore the profile of John M McCurley including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Wei S, McCurley J, Hanlon S, Haigney M
Ann N Y Acad Sci . 2007 Apr; 1099:183-9. PMID: 17446456
Clinical trials suggest females experience less heart failure (HF) progression, mortality, and arrhythmia frequency. HF increases Na/Ca exchanger (NCX) expression and activity contributing to both depressed contractility and ventricular arrhythmias,...
2.
Wei S, Ruknudin A, Shou M, McCurley J, Hanlon S, Elgin E, et al.
Circulation . 2007 Mar; 115(10):1225-33. PMID: 17339552
Background: The Na-Ca exchanger (NCX) is a critical calcium efflux pathway in excitable cells, but little is known regarding its autonomic regulation. Methods And Results: We investigated beta-adrenergic receptor and...
3.
McCurley J, Hanlon S, Wei S, Wedam E, Michalski M, Haigney M
J Am Coll Cardiol . 2004 Sep; 44(6):1301-7. PMID: 15364336
Objectives: We tested the hypothesis that furosemide accelerates the progression of left ventricular systolic dysfunction in a tachycardia-induced porcine model of heart failure. Background: Furosemide activates the renin-angiotensin-aldosterone system in...
4.
Wei S, Ruknudin A, Hanlon S, McCurley J, Schulze D, Haigney M
Circ Res . 2003 Apr; 92(8):897-903. PMID: 12676818
The sodium-calcium exchanger (NCX) protein is the major cardiac calcium extrusion mechanism and is upregulated in heart failure (HF). NCX expression level and functional activity as regulated by beta-adrenergic receptor...